134644-00-1Relevant articles and documents
Copper- versus palladium-catalyzed aromatization of 2-(methoxycarbonyl) tetralones: Synthesis of methyl 1-hydroxy-2-naphthoates
Cívicos, José F.,Ribeiro, Carlos M.R.,Costa, Paulo R.R.,Nájera, Carmen
, p. 1897 - 1902 (2016/04/05)
The aromatization of α-tetralones substituted at the β-position by an ester group is reported using either CuI or Pd2(dba)3. In the case of using CuI (10 mol %) as catalyst and Cs2CO3 as base in dioxane, 2-(methoxycarbonyl)-α-tetralones are smoothly converted into the corresponding methyl 1-hydroxy-2-naphthoates at 70 °C under air. Alternatively, Pd2(dba)3 (1.25 mol %) can also be used as catalyst in the presence of K3PO4 as base in toluene also at 70 °C under argon. These are the most straightforward methodologies for the aromatization of these types of α-tetralones. CuI is the catalyst of choice due to higher efficiency, economical and practical reasons.
α-Hydroxylation of 1,3-dicarbonyl compounds catalyzed by polymer-incarcerated gold nanoclusters with molecular oxygen
Miyamura, Hiroyuki,Kobayashi, Shu
, p. 976 - 978 (2012/10/30)
α-Hydroxylation of 1,3-dicarbonyl compounds was successfully catalyzed by carbon-stabilized polymer-incarcerated gold nanoclusters (PI/CB-Au). The reaction proceeded under mild conditions using molecular oxygen as oxidant with wide substrate scopes and the catalyst could be recovered and reused by a simple operation. The control experiments and the reaction monitoring revealed that α-peroxide compounds were reaction intermediates, and PI/CB-Au also catalyzed isomerization.
