7442-52-6

Basic information

• Product Name: METHYL 1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE
• Synonyms: METHYL 1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE;2-Naphthalenecarboxylic acid, 1,2,3,4-tetrahydro-1-oxo-, Methyl ester;1-OXO-1,2,3,4-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTER;1,2,3,4-tetrahydro-1-oxo-2-Naphthalenecarboxylic acid methyl ester;1,2,3,4-tetrahydro-2-carbomethoxy-1-oxonaphthalene;methyl 1-oxo-3,4-dihydro-2H-naphthalene-2-carboxylate
• CAS NO: 7442-52-6
• Molecular Formula: C₁₂H₁₂O₃
• Molecular Weight: 204.22
• Mol File: 7442-52-6.mol
• Article Data: 52

Chemical Properties

• Melting Point: 84.5-86.5 °C
• Boiling Point: 319.7°C at 760 mmHg
• Flash Point: 140.5°C
• Appearance: /
• Density: 1.198g/cm³
• Vapor Pressure: 0.000334mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.67±0.20(Predicted)
• CAS DataBase Reference: METHYL 1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE(7442-52-6)
• EPA Substance Registry System: METHYL 1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE(7442-52-6)

Safety Data

• Hazardous Substances Data: 7442-52-6(Hazardous Substances Data)

Usage

General Description

METHYL 1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE is a chemical compound with the molecular formula C13H14O3. It is a methyl ester of 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid. This chemical is commonly used as an intermediate in the synthesis of pharmaceutical compounds and other organic chemicals. It is also used as a flavoring agent in the food industry and as a fragrance ingredient in the cosmetic and personal care products. Additionally, it has potential applications in the research and development of new materials and compounds.

InChI:InChI=1/C12H12O3/c1-15-12(14)10-7-6-8-4-2-3-5-9(8)11(10)13/h2-5,10H,6-7H2,1H3

Upstream product

• 57763-56-1 methyl 1,2,3,4-tetrahydro-1-oxo-2-naphthaleneglyoxalate 
• 67-56-1 methanol 
• 57663-21-5 2-bis(methylthio)methylene-1-tetralone 
• 95447-99-7 1-tert-Butylamino-3,4-dihydro-naphthalene-2-carboxylic acid methyl ester 
• 101681-26-9 C₁₅H₁₈O₂S₂ 
• 139005-16-6 2-Dimethylaminomethyl-1-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 616-38-6 carbonic acid dimethyl ester 
• 17640-15-2 methyl cyanoformate 
• 134644-00-1 methyl 2-hydroxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate 
• 36919-03-6 methyl pentafluorophenyl carbonate 
• 1829-28-3 ethyl 2-iodobenzoate 

Downstream Products

• 102079-10-7 2-(2-cyano-benzyl)-1-oxo-1,2,3,4-tetrahydro-[2]naphthoic acid methyl ester 
• 10345-67-2 2-(hydroxymethyl)-3,4-dihydronaphthalen-1(2H)-one 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 283174-81-2 (-)-menthyl 1-tetralone-2-carboxylate 
• 685139-92-8 (1S)-2-oxo-1-(3-phenylallyl)-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid methyl ester 

Relevant articles and documents

Dynamic Kinetic Sensitization of β-Dicarbonyl Compounds—Access to Medium-Sized Rings by De Mayo-Type Ring Expansion

Herein, we present a photocatalyzed two-carbon ring expansion of β-dicarbonyl compounds with unactivated olefins that provides facile access to medium-sized rings. Selective sensitization of the substoichiometric enol tautomer enables reactivity of substr

Palladium Catalyzed Ring Expansion Reaction of Isoxazolones with Isocyanides: Synthesis of 1,3-Oxazin-6-One Derivatives

A palladium catalyzed ring expansion reaction of isoxazolones with isocyanides was disclosed. In the reaction, a cascade process involving ring-opening/cyclization was suggested. The reaction features high atomic economy due to no elimination of CO2 occurred. Moreover, products obtained demonstrate aggregation-induced emission properties with relatively high solid-state emission efficiencies. (Figure presented.).

Highly Carbon-Selective Monofluoromethylation of β-Ketoesters with Fluoromethyl Iodide

A highly carbon-selective monofluoromethylation of a broad range of β-ketoesters with fluoromethyl iodide under mild conditions is described. The uses of lithium tert-butoxide as the base and diglyme as the solvent made great contributions to the high C/O regioselectivity.