1346523-56-5

Basic information

• Product Name: 7-[ethyl-(4-methanesulfonylphenyl)amino]-4-methylcoumarin
• Synonyms: 7-[ethyl-(4-methanesulfonylphenyl)amino]-4-methylcoumarin
• CAS NO: 1346523-56-5
• Molecular Weight: 357.43
• Mol File: 1346523-56-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-[ethyl-(4-methanesulfonylphenyl)amino]-4-methylcoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[ethyl-(4-methanesulfonylphenyl)amino]-4-methylcoumarin(1346523-56-5)
• EPA Substance Registry System: 7-[ethyl-(4-methanesulfonylphenyl)amino]-4-methylcoumarin(1346523-56-5)

Safety Data

• Hazardous Substances Data: 1346523-56-5(Hazardous Substances Data)

Upstream product

• 3743-29-1 N-(3-hydroxyphenyl)-4-methylbenzenesulfonamide 
• 74-96-4 ethyl bromide 
• 101973-09-5 7-[N-(p-toluenesulfonyl)amino]-4-methylcoumarin 
• 7159-96-8 ethyl N-(3-hydroxyphenyl)carbamate 
• 591-27-5 m-Hydroxyaniline 
• 98-59-9 p-toluenesulfonyl chloride 
• 75-03-6 ethyl iodide 
• 58632-48-7 (4-methyl-2-oxo-2H-1-benzopyran-7-yl)carbamic acid ethyl ester 
• 26093-31-2 7-amino-4-methylcoumarin. 

Downstream Products

• 1346523-59-8 4-{[ethyl-(4-methylcoumarin-7-yl)amino]methyl}benzoic acid methyl ester 
• 1346523-61-2 4-{[ethyl-(4-methylcoumarin-7-yl)amino]methyl}benzoic acid 
• 28821-18-3 4-methyl-7-ethylamino-2H-benzopyran-2-one 
• 1372874-79-7 C₁₉H₁₉NO₅S 

Relevant articles and documents

7-Amino coumarin based fluorescent phototriggers coupled with nano/bio-conjugated bonds: Synthesis, labeling and photorelease

By several synthetic pathways, we designed and synthesized a new series of unsymmetrical substituted 7-amino coumarin-based phototriggers with various nano/bio-conjugated bonds. The photophysical properties of most of the substituted coumarin-based phototriggers, except for compound P9 with maleimide group, showed no significant change compared with that of 7-(diethylamino)-4- (hydroxylmethyl) coumarin (DEACM-OH, the reported symmetric substituted 7-amine coumarin based phototrigger). Four compounds (P2, P4, P9, 14) were successfully conjugated with typical carriers such as mesoporous silica nanoparticles, biocompatible polymer PEG and common protein BSA, respectively. The efficient photorelease of ibuprofen (IBU) in the model cargo delivery system of MD4 confirmed that our designed phototriggers could serve well as a photo-cage for bioactive molecules and the release can be regulated precisely by manipulating the external irradiation conditions. All the results hinted at the superiority of using these coumarin functional compounds for photo-regulated release in biotechnology and biomedical areas. The Royal Society of Chemistry 2012.