1346964-85-9

Basic information

• Product Name: (E)-1-(2-bromo-4-methylphenyl)pent-3-en-2-one
• CAS NO: 1346964-85-9
• Molecular Weight: 253.139
• Mol File: 1346964-85-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(2-bromo-4-methylphenyl)pent-3-en-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(2-bromo-4-methylphenyl)pent-3-en-2-one(1346964-85-9)
• EPA Substance Registry System: (E)-1-(2-bromo-4-methylphenyl)pent-3-en-2-one(1346964-85-9)

Safety Data

• Hazardous Substances Data: 1346964-85-9(Hazardous Substances Data)

Upstream product

• 1346964-52-0 1-(2-bromo-4-methylphenyl)pent-4-en-2-one 
• 824-54-4 2-bromo-4-methylbenzaldehyde 
• 824-53-3 2,6-dibromo-4-methylbenzyl alcohol 
• 75366-14-2 1-(bromomethyl)-2-bromo-4-methylbenzene 

Relevant articles and documents

Synthesis of 2-naphthols via carbonylative stille coupling reaction of 2-bromobenzyl bromides with tributylallylstannane followed by the heck reaction

A method for the synthesis of 2-naphthols 4 is described. The carbonylative Stille coupling reactions of 2-bromobenzyl bromides with tributylallylstannane to produce 2-bromobenzyl β,γ-unsaturated ketones 2 in satisfactory to excellent yields has been achieved. The isomerization of 2-bromobenzyl β,γ-unsaturated ketones 2 can readily occur under basic conditions to generate 2-bromobenzyl α,β-unsaturated ketones 3. The 2-bromobenzyl α,β-unsaturated ketones 3 can be transformed into 2-naphthols 4 via intramolecular Heck reaction in satisfactory to good yields (Figure presented).