1347750-79-1 Usage
Description
Thiol-dPEG5-azido is a versatile chemical compound consisting of a thiol functional group, a polyethylene glycol (dPEG5) spacer, and an azido functional group. The thiol group allows for covalent bonding with gold surfaces and other thiol-reactive surfaces, making it suitable for bioconjugation and surface functionalization. The dPEG5 spacer enhances flexibility and solubility, while the azido group enables selective reactions with alkynes or other functional groups through copper-catalyzed azide-alkyne cycloaddition (CuAAC) chemistry. This combination of features makes Thiol-dPEG5-azido a valuable compound for applications in chemical biology, diagnostics, and materials science.
Uses
Used in Chemical Biology:
Thiol-dPEG5-azido is used as a bioconjugation agent for attaching biomolecules to surfaces or other molecules, facilitating the study of biological processes and the development of new therapeutic agents.
Used in Diagnostics:
Thiol-dPEG5-azido is used as a component in the development of diagnostic tools, such as sensors and imaging agents, due to its ability to selectively react with other functional groups and its solubility-enhancing properties.
Used in Materials Science:
Thiol-dPEG5-azido is used as a surface functionalization agent to modify the properties of materials, such as improving biocompatibility or enhancing specific interactions with other molecules, through the formation of covalent bonds with gold surfaces or other thiol-reactive surfaces.
Used in Drug Delivery Systems:
Thiol-dPEG5-azido is used as a component in the design of drug delivery systems, allowing for the attachment of therapeutic agents to carriers or surfaces, improving the targeting and release of drugs in a controlled manner.
Used in Bioorthogonal Chemistry:
Thiol-dPEG5-azido is used as a reactant in bioorthogonal chemistry, enabling the selective labeling or modification of biomolecules within complex biological systems without interfering with native biochemical reactions, thanks to the copper-catalyzed azide-alkyne cycloaddition (CuAAC) chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1347750-79-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,7,7,5 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1347750-79:
(9*1)+(8*3)+(7*4)+(6*7)+(5*7)+(4*5)+(3*0)+(2*7)+(1*9)=181
181 % 10 = 1
So 1347750-79-1 is a valid CAS Registry Number.
1347750-79-1Relevant articles and documents
Interfacial strain-promoted alkyne-azide cycloaddition (I-SPAAC) for the synthesis of nanomaterial hybrids
Gobbo, Pierangelo,Novoa, Samantha,Biesinger, Mark C.,Workentin, Mark S.
, p. 3982 - 3984 (2013)
An interfacial strain promoted azide-alkyne cycloaddition (I-SPACC) is introduced as a method to prepare robust nanomaterial hybrids. This is demonstrated with a reaction between a novel dibenzocyclooctyne-modified single walled carbon nanotubes (DBCO-SWC
