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135-07-9

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135-07-9 Usage

Description

Methyclothiazide, a derivative of Hydrochlorothiazide, is a diuretic medication that functions by increasing the amount of urine produced and excreted, thereby helping to remove excess fluid and salt from the body. It is characterized by its effectiveness in treating conditions like congestive heart failure and hypertension, and is known for its use in both hospital and personal settings.

Uses

Used in Pharmaceutical Industry:
Methyclothiazide is used as an antihypertensive agent for the treatment of high blood pressure. It helps in reducing the strain on the heart and blood vessels by promoting the excretion of excess fluid and salt, thus lowering blood pressure.
Used in Cardiology:
Methyclothiazide is used as a diuretic for the management of congestive heart failure. It aids in alleviating the symptoms of heart failure by removing excess fluid that can cause shortness of breath, leg swelling, and fatigue.
Used in Hospital Settings:
Methyclothiazide is utilized as a therapeutic agent in hospitals to treat patients with conditions that require fluid and electrolyte balance regulation, such as edema and hypertension.
Used for Personal Use:
Methyclothiazide is also used by individuals under the guidance of healthcare professionals for the self-management of conditions like high blood pressure and fluid retention, providing convenience and accessibility for personal healthcare needs.
Brand names:
Aquatensen (Medpointe) and Enduron (Abbott) are some of the brand names under which Methyclothiazide is marketed and distributed for its various applications in the medical field.

Check Digit Verification of cas no

The CAS Registry Mumber 135-07-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 135-07:
(5*1)+(4*3)+(3*5)+(2*0)+(1*7)=39
39 % 10 = 9
So 135-07-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H11Cl2N3O4S2/c1-14-9(4-10)13-6-2-5(11)7(19(12,15)16)3-8(6)20(14,17)18/h2-3,9,13H,4H2,1H3,(H2,12,15,16)

135-07-9 Well-known Company Product Price

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  • USP

  • (1424007)  Methyclothiazide  United States Pharmacopeia (USP) Reference Standard

  • 135-07-9

  • 1424007-200MG

  • 4,662.45CNY

  • Detail

135-07-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-1λ<sup>6</sup>,2,4-benzothiadiazine-7-sulfonamide

1.2 Other means of identification

Product number -
Other names Methycyclothiazide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:135-07-9 SDS

135-07-9Related news

Direct vascular actions of Methyclothiazide (cas 135-07-9) in remodeled mesenteric arteries from hypertensive patients09/30/2019

In vitro experiments were designed to assess the inhibitory effect of the thiazide diuretic methyclothiazide (MCTZ) on contractile responses to norepinephrine (NE) of mesenteric rings from hypertensive patients and normotensive controls. Arteries were taken from portions of mesocolon from 24 pat...detailed

Effect on rat aortas of Methyclothiazide (cas 135-07-9) and indapamide comparison with hydroclorothiazide09/29/2019

Data concerning a vasorelaxant direct action of thiazide diuretics are scarse and controversial. The aim of the present work was to assess and to compare the vascular relaxation induced by indapamide (I), methyclothiazide (MT) and hydrochlorothiazide (H).Aortas from spontaneously hypertensive a...detailed

Statistical optimization of a reversed-phase liquid chromatographic method for the determination of amiloride and Methyclothiazide (cas 135-07-9) in tablets10/01/2019

A quantitative high-performance liquid chromatographic method in which amiloride is separated from methylclothiazide on a C 18 column with detection at 286 nm was developed with the aid of the ‘window diagram’ technique of Laub and Purnell. The effect of simultaneously varying the pH a...detailed

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