135066-29-4

Basic information

• Product Name: 2-(4-fluorophenyl)-1H-indazol-3(2H)-one
• Synonyms: 2-(4-fluorophenyl)-1H-indazol-3(2H)-one
• CAS NO: 135066-29-4
• Molecular Weight: 228.226
• Mol File: 135066-29-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-1H-indazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-1H-indazol-3(2H)-one(135066-29-4)
• EPA Substance Registry System: 2-(4-fluorophenyl)-1H-indazol-3(2H)-one(135066-29-4)

Safety Data

• Hazardous Substances Data: 135066-29-4(Hazardous Substances Data)

Upstream product

• 586-96-9 Nitrosobenzene 
• 371-40-4 4-fluoroaniline 
• 13939-06-5 molybdenum hexacarbonyl 
• 1545-83-1 4-fluoroazobenzene 
• 135066-26-1 N-(4-fluorophenyl)-2-nitrobenzamide 

Relevant articles and documents

Palladium-Catalyzed Carbonylative Cyclization of Azoarenes

In this communication, we established an interesting palladium-catalyzed carbonylation protocol for the intramolecular cyclization of azoarenes. With Mo(CO)6 as the solid CO source and through C(sp2)?H bond activation, a series of azoarenes were transformed into the corresponding 2-arylindazolones in moderate to good yields. Notably, not only symmetrical azoarenes, but also unsymmetrical substrates underwent the reaction with excellent regioselectivity.

A convenient synthesis of 2-arylindazol-3-ones

The reductive cyclisation of o-nitrobenzanilides with zinc and sodium hydroxide in aqueous methanol provides a convenient source of 2-arylindazol-3-ones.