135082-46-1

Basic information

• Product Name: 6-(benzyloxy)-10-methyl-1,2,3,4,5-pentamethoxyacridin-9-one
• Synonyms: 6-(benzyloxy)-10-methyl-1,2,3,4,5-pentamethoxyacridin-9-one
• CAS NO: 135082-46-1
• Molecular Weight: 465.503
• Mol File: 135082-46-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-(benzyloxy)-10-methyl-1,2,3,4,5-pentamethoxyacridin-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(benzyloxy)-10-methyl-1,2,3,4,5-pentamethoxyacridin-9-one(135082-46-1)
• EPA Substance Registry System: 6-(benzyloxy)-10-methyl-1,2,3,4,5-pentamethoxyacridin-9-one(135082-46-1)

Safety Data

• Hazardous Substances Data: 135082-46-1(Hazardous Substances Data)

Upstream product

• 584-08-7 potassium carbonate 
• 135082-45-0 6-(benzyloxy)-1,2,3,4,5-pentamethoxyacridin-9-one 
• 74-88-4 methyl iodide 
• 135082-42-7 4-(benzyloxy)-3-methoxy-N-(2,3,4,5-tetramethoxyphenyl)anthranilic acid 
• 23938-73-0 2-amino-3-methoxy-4-benzyloxybenzoic acid 
• 3584-32-5 4-(benzyloxy)-3-methoxy-2-nitrobenzoic acid 

Downstream Products

• 142003-90-5 3-(benzyloxy)-5-methyl-4,6,7-trimethoxyquino<3,2-a>phenazin-14(5H)-one 
• 142003-89-2 6-(benzyloxy)-3,4-dimethoxy-10-methylacridine-1,2,9-trione 
• 142003-88-1 6-(benzyloxy)-2,3-dimethoxy-10-methylacridine-1,4,9-trione 
• 135082-47-2 6-(benzyloxy)-1-hydroxy-10-methyl-2,3,4,5-tetramethoxyacridin-9-one 
• 82354-35-6 des-N-methylnoracronycine 

Relevant articles and documents

Multisubstituted 1-hydroxy-9-acridones with anticancer activity

The present invention provides a compound having the structure: STR1 The present invention also provides a method for synthesizing a compound having the above-identified structure as well as the intermediate compounds produced according to that method. The present invention further provides a pharmaceutical composition comprising the above compounds. Lastly, the present invention provides a method of inhibiting growth of tumor cells.

SYNTHESIS OF GLYFOLINE, A CONSTITUENT OF GLYCOSMIS CITRIFOLIA (WILLD.) LINDL. AND A POTENTIAL ANTICANCER AGENT

Condensation of 4-benzyloxy-3-methoxyanthranilic acid (3) with 5-iodo-1,2,3,4-tetramethoxybenzene (4) gave 6-benzyloxy-1,2,3,4,5-pentamethoxy-9-acridone (7), which was then converted into glyfoline (1) via N-methylation, selective de-O-methylation, and de