13524-04-4Relevant articles and documents
Synthesis, Structure, Reactivity, and Catalytic Activity of Cyclometalated (Phosphine)- and (Phosphinite)ruthenium Complexes
Sun, Ruichen,Chu, Xiaodan,Zhang, Shaowei,Li, Tongyu,Wang, Zhuo,Zhu, Bolin
, p. 3174 - 3183 (2017)
Reactions of naphthyl- and o-methylphenyl-substituted phosphines with [RuCl2(p-cymene)]2 resulted in the corresponding phosphine-substituted ruthenium dichlorides (1a,b and 3). When the reactions of aryl-substituted phosphines or pho
Cyclometalated ruthenium(II) complexes as highly active transfer hydrogenation catalysts
Baratta, Walter,Da Ros, Paolo,Del Zotto, Alessandro,Sechi, Alessandra,Zangrando, Ennio,Rigo, Pierluigi
, p. 3584 - 3588 (2004)
Quantitative conversion: Reaction of the 14-electron complex [RuCl 2{(2,6-Me2C6H3)PPh2} 2] with CH2O in the presence of NEt3 gave a five-coordinate cyclometalated complex with a δ-agostic interaction of one ortho-methyl group (see X-ray crystal structure), Displacement of one phosphane group with 2-(amino-methyl)pyridine gave a highly active catalyst for the quantitative conversion of ketones into alcohols.
Uncatalyzed hydrogen-transfer reductions of aryl ketones
Srinivasan,Manisankar
, p. 1338 - 1347 (2011)
A simple, convenient, and environmentally benign procedure has been developed for exclusive reduction of aryl ketones by hydrogen transfer with sec-BuOH as hydrogen donor in the presence of KOH without supercritical conditions, ligands, and any catalytic utility.
Synthesis of 2-aminomethylpiperidine ruthenium(II) phosphine complexes and their applications in transfer hydrogenation of aryl ketones
Tuerkmen, Hayati
, p. 731 - 735 (2012)
The complex trans,cis-[RuCl2(PPh3)2(ampi)] (2) was prepared by reaction of RuCl2(PPh3)3 with 2-aminomethylpiperidine(ampi) (1). [RuCl2(PPh 2(CH2)nPPh2)(ampi) (n = 3, 4, 5)] (3-5) were synthesized by displacement of two PPh3 with chelating phosphine ligands. All complexes (2-5) were characterized by 1 H, 13C, 31P NMR, IR and UV-visible spectroscopy and elemental analysis. They were found to be efficient catalysts for transfer hydrogen reactions. Copyright
Enhancing cofactor regeneration of cyanobacteria for the light-powered synthesis of chiral alcohols
Fan, Jianhua,Zhang, Yinghui,Wu, Ping,Zhang, Xiaoyan,Bai, Yunpeng
, (2021/11/24)
Cyanobacteria Synechocystis sp. PCC 6803 was exploited as green cell factory for light-powered asymmetric synthesis of aromatic chiral alcohols. The effect of temperature, light, substrate and cell concentration on substrate conversions were investigated. Under the optimal condition, a series of chiral alcohols were synthesized with conversions up to 95% and enantiomer excess (ee) > 99%. We found that the addition of Na2S2O3 and Angeli's Salt increased the NADPH content by 20% and 25%, respectively. As a result, the time to reach 95% substrate conversion was shortened by 12 h, which demonstrated that the NADPH regeneration and hence the reaction rates can be regulated in cyanobacteria. This blue-green algae based biocatalysis showed its potential for chiral compounds production in future.
Manganese-catalyzed homogeneous hydrogenation of ketones and conjugate reduction of α,β-unsaturated carboxylic acid derivatives: A chemoselective, robust, and phosphine-free in situ-protocol
Topf, Christoph,Vielhaber, Thomas
, (2021/07/10)
We communicate a user-friendly and glove-box-free catalytic protocol for the manganese-catalyzed hydrogenation of ketones and conjugated C[dbnd]C[sbnd]bonds of esters and nitriles. The respective catalyst is readily assembled in situ from the privileged [Mn(CO)5Br] precursor and cheap 2-picolylamine. The catalytic transformations were performed in the presence of t-BuOK whereby the corresponding hydrogenation products were obtained in good to excellent yields. The described system offers a brisk and atom-efficient access to both secondary alcohols and saturated esters avoiding the use of oxygen-sensitive and expensive phosphine-based ligands.
Synthesis and structural elucidation of (pyridyl)imine Fe(II) complexes and their applications as catalysts in transfer hydrogenation of ketones
Tsaulwayo, Nokwanda,Kumah, Robert T.,Ojwach, Stephen O.
, (2021/01/25)
Reactions of (pyridyl)imine ligands: 2,6-diisopropyl-N-[(pyridine-2-yl)methylene]aniline (L1), 2,6-diisopropyl-N-[(pyridine-2-yl)ethylidene]aniline (L2), 2,6-dimethyl-N-[(pyridine-2-yl)methylene]aniline (L3), 2,6-dimethyl-N-[(pyridine-2-yl)ethylidene]aniline (L4) and N-[(pyridine-2-yl)methylene]aniline (L5) with FeCl2 salt afforded the corresponding paramagnetic Fe(II) complexes [Fe(L1)2Cl][FeCl4] (Fe1), [Fe(L2)2Cl][FeCl4] (Fe2), [Fe(L3)2Cl][FeCl4] (Fe3), [Fe(L4)2Cl][FeCl4], (Fe4), [Fe(L5)2Cl2] (Fe5) in good yields. On the other hand, reactions of L1 with FeCl2 in the presence of NaPF6 afforded complex [Fe(L1)2Cl][PF6] (Fe6) in moderate yields. Molecular structures of complexes Fe1 and Fe2 reveal the formation of cationic species containing two N^N bidentate ligands and one chlorido co-ligand to give five-coordinate geometry with [FeCl4]? as counter-anion. On the other hand, complex Fe5, is an octahedral neutral species containing two bidentate L5 and two chlorido ligands. All the complexes (Fe1–Fe6) formed active catalysts in the transfer hydrogenation of ketones affording average yields of about 85%. The ligand architecture, reaction conditions and nature of substrate influenced the catalytic activities of the complexes. Mercury and subs-stoichiometric poisoning tests pointed to the existence of both Fe(0) nanoparticles and homogeneous Fe(II) species as the active intermediates.
