1353155-66-4

Basic information

• Product Name: N’-(hydrazinecarbonyl)-2-[(2-methyl-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy)]acetohydrazide
• Synonyms: N’-(hydrazinecarbonyl)-2-[(2-methyl-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy)]acetohydrazide
• CAS NO: 1353155-66-4
• Molecular Weight: 396.406
• Mol File: 1353155-66-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N’-(hydrazinecarbonyl)-2-[(2-methyl-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy)]acetohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N’-(hydrazinecarbonyl)-2-[(2-methyl-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy)]acetohydrazide(1353155-66-4)
• EPA Substance Registry System: N’-(hydrazinecarbonyl)-2-[(2-methyl-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy)]acetohydrazide(1353155-66-4)

Safety Data

• Hazardous Substances Data: 1353155-66-4(Hazardous Substances Data)

Upstream product

• 5060-53-7 8-hydroxy-2-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone 
• 1319735-76-6 ethyl 2-[3,4-dihydro-2-methyl-3-(2-methylphenyl)-4-oxoquinazolin-8-yloxy]acetate 
• 1319735-77-7 2-[3,4-dihydro-2-methyl-3-(2-methylphenyl)-4-oxoquinazolin-8-yloxy]acetic acid hydrazide 
• 1353155-58-4 ethyl 2-[2-(2-methyl)-3-(2-methylphenyl)-4(3H)-(quinazolin-8-yloxy)acetyl]hydrazinecarboxylate 

Relevant articles and documents

Synthesis and anticonvulsant evaluation of some new 2,3,8-trisubstituted- 4(3H)-quinazoline derivatives

A new series of 2,3,8-trisubstituted-4(3H)-quinazoline derivatives were synthesized, evaluated for their anticonvulsant activity against electrically (MES) and chemically (PTZ, picrotoxin and Strychnine) induced seizures and compared with the standard drugs methaqualone and sodium valproate. Compounds 3, 17 and 22 proved to be the most potent compounds of this series with relatively low neurotoxicity and low toxicity in the median lethal dose test as compared with the reference drugs. The obtained results showed that the most active compounds could be useful as a template for future design, modification and investigation to produce more active analogs.