135357-90-3

Basic information

• Product Name: (2R)-N-benzyl-2-amino-2-phenyl-1-ethanol
• Synonyms: (2R)-N-benzyl-2-amino-2-phenyl-1-ethanol
• CAS NO: 135357-90-3
• Molecular Weight: 227.306
• Mol File: 135357-90-3.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: (2R)-N-benzyl-2-amino-2-phenyl-1-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-N-benzyl-2-amino-2-phenyl-1-ethanol(135357-90-3)
• EPA Substance Registry System: (2R)-N-benzyl-2-amino-2-phenyl-1-ethanol(135357-90-3)

Safety Data

• Hazardous Substances Data: 135357-90-3(Hazardous Substances Data)

Upstream product

• 20989-17-7 (2S)-2-phenylglycinol 
• 100-47-0 benzonitrile 
• 100-44-7 benzyl chloride 
• 100-52-7 benzaldehyde 
• 670278-81-6 methyl N-benzyl-(S)-α-phenylglycinate 
• 98-88-4 benzoyl chloride 
• 2935-35-5 (S)-2-phenylglycine 
• 7352-07-0 N-benzoyl-α-phenylglycine 
• 74879-43-9 (S)-2-Phenyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-ethanol 

Downstream Products

• 462871-24-5 (S)-3-Benzyl-4-phenyl-oxazolidine 
• 1201574-96-0 3-{benzyl[(1S)-2-hydroxy-1-phenylethyl]amino}propanenitrile 
• 1421593-15-8 (2S)-2-{benzyl[2-(benzyl{(1S)-2-[(diphenylphosphanyl)oxy]-1-phenylethyl}amino)ethyl]amino}-2-phenylethyl diphenylphosphinite 
• 1421593-11-4 (2S)-2-[benzyl(2-{benzyl[(1S)-2-hydroxy-1-phenylethyl]amino}ethyl)amino]-2-phenylethan-1-ol 
• 142342-61-8 (S)-3-[Benzyl-((S)-2-hydroxy-1-phenyl-ethyl)-amino]-butyric acid ethyl ester 
• 142342-69-6 (R)-3-[Benzyl-((S)-2-hydroxy-1-phenyl-ethyl)-amino]-butyric acid ethyl ester 
• 563539-37-7 (2E,4S)-4-(benzyl-cyanomethyl-amino)-4-phenyl-but-2-enoic acid ethyl ester 
• 462871-85-8 [Benzyl-((R)-2-chloro-2-phenyl-ethyl)-amino]-acetic acid ethyl ester 
• 462871-29-0 {[benzyl-(2-hydroxy-1S-phenyl-ethyl)-amino]methyl}-phosphonic acid diethyl ester 

Relevant articles and documents

Microwave-Assisted CuCl-Catalyzed Three-Component Reactions of Alkynes, Aldehydes, and Amino Alcohols

A microwave (MW)-assisted three-component coupling of amino alcohols, aldehydes, and alkynes is developed under catalysis by CuCl. Compared with thermal conditions, MW irradiation greatly increases the reaction efficiency. The reactions of various primary N -alkyl/arylamino alcohols, aliphatic/aromatic aldehydes, and alkynes are systematically investigated, affording the desired products in moderate to good yields. Notably, acetylene is also an effective reactant under the current MW-assisted conditions.

Cobalt complex, preparation method thereof, and application thereof in selective catalysis of transfer hydrogenation reaction of cyano group

The invention discloses a cobalt complex, a preparation method thereof, and an application thereof in the selective catalysis of a transfer hydrogenation reaction of a cyano group. The structural formula of the cobalt complex is represented by formula I. The cobalt complex is prepared through a reaction of a cobalt salt and an NNP ligand or a PNP ligand under the protection of an inert atmosphere;and the chemical formula of the cobalt salt is CoX12, wherein X1 represents halogen, a sulfate radical, a perchlorate radical, a hexafluorophosphate radical, a hexafluoroantimonate radical, a tetrafluoroborate radical, a trifluoromethanesulfonate radical or a tetra(pentafluorophenyl)borate radical. The cobalt complex can be used in the selective catalysis of the transfer hydrogenation reaction ofthe cyano group to obtain a primary amine compound, a secondary amine compound and a tertiary amine compound, the primary amine compound, the secondary amine compound and the tertiary amine compoundare important intermediates in a series of subsequent functionalizing reactions, and the cobalt complex has a very high catalysis activity, and has great research values and a great application prospect.

Design and synthesis of enantiomeric (R)- and (S)-copper(II) and diorganotin(IV)-based antitumor agents: Their in vitro DNA binding profile, cleavage efficiency and cytotoxicity studies

New chiral reduced Schiff base ligands (R)/(S)-2-(2-hydroxy-1- phenylethylaminomethyl)phenol (L), (R)/(S)-2-(benzylamino)-2-phenylethanol (L′) and their Cu(II)/organotin(IV) complexes (1-4) were synthesized and thoroughly characterized. Preliminary in vit