670278-81-6

Basic information

• Product Name: methyl N-benzyl-(S)-α-phenylglycinate
• Synonyms: methyl N-benzyl-(S)-α-phenylglycinate
• CAS NO: 670278-81-6
• Molecular Weight: 255.316
• Mol File: 670278-81-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: methyl N-benzyl-(S)-α-phenylglycinate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-benzyl-(S)-α-phenylglycinate(670278-81-6)
• EPA Substance Registry System: methyl N-benzyl-(S)-α-phenylglycinate(670278-81-6)

Safety Data

• Hazardous Substances Data: 670278-81-6(Hazardous Substances Data)

Upstream product

• 153924-62-0 N-benzylidenephenylglycine methyl ester 
• 100-52-7 benzaldehyde 
• 24461-61-8 phenylglycine methyl ester 
• 68906-71-8 (benzylidene-amino)-phenyl-acetic acid methyl ester 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 
• 902778-24-9 1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-O-yl α-chloro-α-phenylacetate 
• 100-46-9 benzylamine 
• 100-39-0 benzyl bromide 
• 2912-62-1 α-chlorophenylacetyl chloride 

Downstream Products

• 225645-17-0 (2S)-N-benzyl-N-methyl-2-phenylglycine methyl ester 
• 135357-90-3 (2R)-N-benzyl-2-amino-2-phenyl-1-ethanol 
• 696620-23-2 ((S)-3-Benzylamino-2-oxo-3-phenyl-propyl)-phosphonic acid dimethyl ester 

Relevant articles and documents

Rh-catalyzed asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution

Catalyzed by a rhodium complex of P-stereogenic diphosphine ligand trichickenfootphos (TCFP), asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution has been realized for the preparation of chiral arylglycines with good yields and enantioselectivities.

Facile synthesis of β-amino disulfides, cystines, and their direct incorporation into peptides

Herein, we report a simple and efficient methodology for the synthesis of β-amino disulfides by regioselective ring opening of sulfamidates with benzyltriethylammonium tetrathiomolybdate [BnNEt3] 2MoS4. Stability and reactivity of different protecting groups under the reaction conditions have been discussed. This methodology has also been extended to serine and threonine derived sulfamidates to furnish cystine and 3,3′-dimethyl cystine derivatives. Georg Thieme Verlag.

Asymmetric syntheses of N-substituted α-amino esters via dynamic kinetic resolution of α-haloacyl diacetone-d-glucose

Diacetone-d-glucose or d-allose mediated dynamic kinetic resolution of α-halo esters in nucleophilic substitution reaction has been investigated. Reactions with various amine nucleophiles in the presence of TBAI and DIEA can provide the N-substituted α-am