135484-74-1 Usage
Description
3-Bromo-2-formylaniline is an organic compound with the molecular formula C7H6BrNO. It is characterized by the presence of a bromine atom at the 3-position, a formyl group (aldehyde) at the 2-position, and an aniline group (an amine attached to a benzene ring). 3-Bromo-2-formylaniline is known for its potential applications in various chemical and pharmaceutical processes due to its unique structural features.
Uses
Used in Pharmaceutical Industry:
3-Bromo-2-formylaniline is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for further functionalization and modification, making it a versatile building block for the development of new drugs.
Used in Chemical Synthesis:
In the chemical industry, 3-Bromo-2-formylaniline is used as a starting material for the preparation of aminoquinoline compounds. These compounds have a wide range of applications, including their use as antimalarial, antiprotozoal, and anticancer agents.
Used in Anticancer Applications:
3-Bromo-2-formylaniline is also used in the development of immunoconjugates, which are a type of targeted therapy for cancer treatment. These conjugates combine the targeting ability of antibodies with the cytotoxic properties of drugs, allowing for more precise and effective treatment of cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 135484-74-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,4,8 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 135484-74:
(8*1)+(7*3)+(6*5)+(5*4)+(4*8)+(3*4)+(2*7)+(1*4)=141
141 % 10 = 1
So 135484-74-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrNO/c8-6-2-1-3-7(9)5(6)4-10/h1-4H,9H2
135484-74-1Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS
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, (2022/04/03)
The present invention provides heterocyclic compounds of formula (I), which are therapeutically useful as CBP/EP300 inhibitors. These compounds are useful in the treatment and/or prevention of diseases or disorders mediated by CBP and/or EP300 in an individual. The present invention also provides preparation of the compounds and pharmaceutical compositions comprising at least one of the compounds of formula (I) or a pharmaceutically acceptable salt, or a stereoisomer or a tautomer, an N-oxide or an ester thereof.
Acid-catalysed Cyclisation of o-Sulphonamido Ketene Dithioacetal S-Oxides: A Novel Synthesis of the Indole Ring System
Hewson, Alan T.,Hughes, Kevin,Richardson, Steward K.,Sharpe, David A.,Wadsworth, Alan H.
, p. 1565 - 1569 (2007/10/02)
Treatment of o-sulphonamido aryl ketene dithioacetal S-oxides with hydrochloric acid in the presence of hydrogen sulphide gives 2-methylthioindoles.