181871-83-0 Usage
Description
5-Bromoquinoxalin-2-amine is an organic compound with the molecular formula C8H6BrN3. It is a derivative of quinoxaline, a fused bicyclic compound consisting of a benzene ring and a pyrimidine ring. The presence of a bromine atom at the 5-position and an amino group at the 2-position provides this molecule with unique chemical and biological properties, making it a versatile building block in the synthesis of various pharmaceuticals and bioactive molecules.
Uses
Used in Pharmaceutical Industry:
5-Bromoquinoxalin-2-amine is used as a key intermediate in the synthesis of Tetrazolylarylsulfonamides, which are potent inhibitors of metallo-beta-lactamases. These enzymes are responsible for the resistance of certain bacteria to beta-lactam antibiotics, such as penicillins and cephalosporins. By inhibiting metallo-beta-lactamases, Tetrazolylarylsulfonamides can help restore the effectiveness of these antibiotics and combat antibiotic resistance.
In addition to its application in the pharmaceutical industry, 5-Bromoquinoxalin-2-amine may also find use in other areas of research and development, such as the synthesis of novel compounds with potential applications in materials science, agrochemistry, and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 181871-83-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,8,7 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 181871-83:
(8*1)+(7*8)+(6*1)+(5*8)+(4*7)+(3*1)+(2*8)+(1*3)=160
160 % 10 = 0
So 181871-83-0 is a valid CAS Registry Number.
181871-83-0Relevant articles and documents
Design of triple helix forming C-glycoside molecules
Li, Jian-Sen,Fan, Yun-Hua,Zhang, Yi,Marky, Luis A.,Gold, Barry
, p. 2084 - 2093 (2003)
The modeling, synthesis, and characterization of oligomers containing 2-aminoquinazolin-5-yl 2′-deoxynucleotide residues are reported. The 2-aminoquinazoline residues sequence specifically bind via Hoogsteen base pairing as a third strand in the center of
