135586-42-4

Basic information

• Product Name: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 6-(4-nitrophenyl)-3-(4-pyridinyl)-
• CAS NO: 135586-42-4
• Molecular Formula: C14H8N6O2S
• Molecular Weight: 324.323
• Mol File: 135586-42-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 6-(4-nitrophenyl)-3-(4-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 6-(4-nitrophenyl)-3-(4-pyridinyl)-(135586-42-4)
• EPA Substance Registry System: 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 6-(4-nitrophenyl)-3-(4-pyridinyl)-(135586-42-4)

Safety Data

• Hazardous Substances Data: 135586-42-4(Hazardous Substances Data)

Upstream product

• 36209-51-5 4-amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol 
• 62-23-7 4-nitro-benzoic acid 
• 61019-32-7 potassium 4-pyridinyldithiocarbazate 

Relevant articles and documents

Synthesis of some novel 3-(4-Pyridinyl)-6-aryl-1,2,4-triazolo[3,4-b]-1,3,4- thiadiazoles

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Synthesis of some 1, 2, 4-triazole derivatives and investigation of their fungicidal activities

The synthesis of a series of 3-pyridyl-6-aryl-s-triazolo (3. 4-b) (1, 3. 4) - thiadiazoles are described, synthesis of 3-pyndyl-6-aryl-s-triazolo (3. 4-b) (1, 3, 4) - thiadiazoles (3a-m) have been achieved by the condensation of potassium dithiocarbazinate (1) with hydrazine hydrate and water. was under reflux 8 hours to yield 4-amino-3-pyridyl-5-mercapto-s-triazole (2). followed bv treatment with aromatic acid The compounds (3a-m) were characterized by spectral and elemental analyses. All thirteen compounds have been assayed for their fungicidal activity against P. oryzae. B. cinerea, A. nigar, C. albicans and T. rubrum. Compounds containing aryl substituents at position six and the 1. 2, 4-triazole moiety at position one or two showed reasonable fungicidal activity.

Synthesis and biological activity of some triazolothiadiazoles

The synthesis of a series of novel 3-pyridyl-6-aryl-s-triazolo[3,4-b]-[1,3, 4]-thiadiazoles is described. Fourteen new compounds were synthesized and characterized by spectral and elemental analyses. Some compounds were screened for antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa. Compounds containing aryl substituents at position 6 and the 1,2,4-triazole moiety at position 1 or 2 showed reasonable antibacterial activity.