61019-32-7

Basic information

• Product Name: 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid
• CAS NO: 61019-32-7
• Molecular Formula: C₇H₆N₃OS₂*K
• Molecular Weight: 213.28
• Mol File: 61019-32-7.mol
• Article Data: 45

Chemical Properties

• Density: 1.413g/cm³
• Refractive Index: 1.676
• CAS DataBase Reference: 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid(61019-32-7)
• EPA Substance Registry System: 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid(61019-32-7)

Safety Data

• Hazardous Substances Data: 61019-32-7(Hazardous Substances Data)

Usage

General Description

2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid is a chemical compound with the molecular formula C8H7N3O2S2. It has a complex structure that includes a pyridine ring and carbonyl group as well as a hydrazine and carbodithioic acid group. The compound is used in various research and chemical processes due to its unique properties and potential applications. It is important to handle this compound with care as it may pose health and environmental risks if not used properly. Further investigation and research are needed to fully understand the potential uses and effects of 2-(pyridin-4-ylcarbonyl)hydrazinecarbodithioic acid.

Upstream product

• 54-85-3 isoniazid 
• 75-15-0 carbon disulfide 
• 55-22-1 pyridine-4-carboxylic acid 
• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 1570-45-2 isonicotinic acid ethylester 
• 90322-87-5 1-isonicotinoyl-1H-imidazole 

Downstream Products

• 15264-63-8 5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-thione 
• 36209-51-5 4-amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol 
• 13581-25-4 5-(pyridin-4'-yl)-1,3,4-thiadiazole-2(3H)-thione 
• 15264-63-8 5-(4-pyridinyl)-1,3,4-oxadiazole-2-thiol 
• 80809-41-2 3-(4-pyridyl)-6-amino-s-triazolo<3,4-b>-1,3,4-thiadiazole 
• 13581-25-4 5-mercapto-2-(pyridin-4-yl)-1,3,4-thiadiazole 
• 136025-39-3 6-(2-chlorophenyl)-3-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 478362-76-4 C₁₄H₇ClN₆O₂S 
• 135586-42-4 6-(4-nitrophenyl)-3-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 136025-34-8 3-(pyridin-4-yl)-6-o-tolyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole 
• 136025-35-9 C₁₅H₁₁N₅S 
• 135586-40-2 6-(4-chlorophenyl)-3-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 136025-43-9 C₁₄H₈BrN₅S 
• 135586-39-9 C₁₅H₁₁N₅OS 

Relevant articles and documents

Synthesis and characterization of transition metal complexes of potassium 3-(pyridine-4-carbonylmethyl)-dithiocarbazate

The preparation and characterization of some dipositive metal ion complexes derived from potassium 3-(pyridine-4-carbonylmethyl)-dithiocarbazate (PCDHK) are reported. The solid complexes of the composition ML·nH2O (M=Cu(II), Co(II), Mn(II), Zn(II), Cd(II), Ni(II), Pb(II), L = PCD-2, n = 0, 1, PCD-2= PCDHK-K+-H+) and ML 2·2H2O (M=UO2(IV), L=PCDH-1, PCDH-1=PCDHK-K+) have been characterized by elemental analyses, IR, UV, and 1H NMR spectra. The IR spectral data indicate that PCDHK behaves as either a mononegative or binegative ligand and coordinates in a tridentate or bridging tetradentate manner.

Synthesis, spectral and structural studies of a Mn(II) complex of [N′-(pyridine-4-carbonyl)-hydrazine]-carbodithioic acid ethyl ester and Mn(II) and Ni(II) complexes of [N′-(pyridine-4-carbonyl)-hydrazine]-carbodithioic acid methyl ester

The new complexes [Mn(Hpchce)2(o-phen)], {2[Mn(pchcm)(o-phen)2]}·7H2O and [Ni(Hpchcm)(o-phen)2]Cl·CH3OH with [N′-(pyridine-4-carbonyl)-hydrazine]-carbodithioic acid ethyl ester (H2pchce) and [N′-(pyridine-4-carbonyl)-hydrazine]-carbodithioic acid methyl ester (H2pchcm) have been synthesized, containing o-phenanthroline (o-phen) as a coligand. These ligands and their complexes have been characterized by elemental analyses, IR, magnetic susceptibility and single crystal X-ray data. H2pchce (2), [Mn(Hpchce)2(o-phen)] (3) {2[Mn(pchcm)(o-phen)2]}·7H2O (4) and [Ni(Hpchcm)(o-phen)2]Cl·CH3OH (5) crystallized in the monoclinic system, space group Pc, C2/c, P21/n and P21/n, respectively. The (N, O) donor sites of the bidentate ligands chelate the Mn(II) and Ni(II) centers forming a five-membered CN2OM ring. The resulting complexes are paramagnetic and have a distorted octahedral geometry.

Design, synthesis, antibacterial evaluation, and computational studies of hybrid oxothiazolidin–1,2,4-triazole scaffolds

Bacterial infections are a serious threat to human health due to the development of resistance against the presently used antibiotics. The problem of growing and widespread antibiotic resistance is only getting worse with the shortage of new classes of antibiotics, creating a substantial unmet medical need in the treatment of serious bacterial infections. Therefore, in the present work, we report 18 novel hybrid thiazolidine–1,2,4-triazole derivatives as DNA gyrase inhibitors. The derivatives were synthesized by multistep organic synthesis and characterized by spectroscopic methods (1H and 13C nuclear magnetic resonance and mass spectroscopy). The derivatives were tested for DNA gyrase inhibition, and the result emphasized that the synthesized derivatives have a tendency to inhibit the function of DNA gyrase. Furthermore, the compounds were also tested for antibacterial activity against three Gram-positive (Bacillus subtilis [NCIM 2063], Bacillus cereus [NCIM 2156], Staphylococcus aureus [NCIM 2079]) and two Gram-negative (Escherichia coli [NCIM 2065], Proteus vulgaris [NCIM 2027]) bacteria. The derivatives showed a significant-to-moderate antibacterial activity with noticeable antibiofilm efficacy. Quantitative structure–activity relationship (QSAR), ADME (absorption, distribution, metabolism, elimination) calculation, molecular docking, radial distribution function, and 2D fingerprinting were also performed to elucidate fundamental structural fragments essential for their bioactivity. These studies suggest that the derivatives 10b and 10n have lead antibacterial properties with significant DNA gyrase inhibitory efficacy, and they can serve as a starting scaffold for the further development of new broad-spectrum antibacterial agents.

HERBICIDAL COMPOUNDS

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as herbicides.