1356486-29-7Relevant articles and documents
Synthesis of trifluoromethylated acetylenes via copper-catalyzed trifluoromethylation of alkynyltrifluoroborates
Zheng, Huidong,Huang, Yuanyuan,Wang, Zhiwei,Li, Huaifeng,Huang, Kuo-Wei,Yuan, Yaofeng,Weng, Zhiqiang
, p. 6646 - 6649 (2012)
A new method for the synthesis of trifluoromethylated acetylenes is developed which involves the copper-catalyzed trifluoromethylation of alkynyltrifluoroborates with an electrophilic trifluoromethylating reagent. This method offers significant advantages such as efficiency and mild and base-free reaction conditions. A plausible mechanism is proposed.