1357018-82-6

Basic information

• Product Name: C₂₁H₁₂F₇NO
• Synonyms: C₂₁H₁₂F₇NO
• CAS NO: 1357018-82-6
• Molecular Weight: 427.321
• Mol File: 1357018-82-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₂F₇NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₂F₇NO(1357018-82-6)
• EPA Substance Registry System: C₂₁H₁₂F₇NO(1357018-82-6)

Safety Data

• Hazardous Substances Data: 1357018-82-6(Hazardous Substances Data)

Upstream product

• 294182-06-2 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone 
• 294181-95-6 2-(5-bromopyridine-2-yl)-2,2-difluoroacetic acid ethyl ester 
• 624-28-2 2,5-dibromopyridine 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 294182-28-8 5-bromo-2-((-2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridine 

Downstream Products

• 1340593-62-5 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(trifluoromethyl)phenyl)pyridin-2-yl)propan-2-ol 

Relevant articles and documents

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While the orally-active azoles such as voriconazole and itraconazole are effective antifungal agents, they potently inhibit a broad range of off-target human cytochrome P450 enzymes (CYPs) leading to various safety issues (e.g., drug-drug interactions, li

METALLOENZYME INHIBITOR COMPOUNDS

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.