1361119-39-2Relevant articles and documents
A metal-free oxidative amination of benzoxazoles with primary amines and ammonia
Kloeckner, Ulrich,Weckenmann, Nicole M.,Nachtsheim, Boris J.
supporting information; experimental part, p. 97 - 100 (2012/02/03)
An efficient synthesis of 2-aminobenzoxazoles is described by a direct oxidative amination of unfunctionalized benzoxazoles with primary amines. The reaction could be performed in the absence of transition metals by using catalytic amounts of a quaternary ammonium iodide and tert-butylhydroperoxide as a cheap and easy-to-handle co-oxidant. In addition to primary amines, aqueous solutions of NH3 were used to introduce a primary amine group into the heterocyclic core. Georg Thieme Verlag Stuttgart. New York.
