1361519-51-8Relevant articles and documents
Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds
Dantas De Araujo, Aline,Christensen, Caspar,Buchardt, Jens,Kent, Stephen B. H.,Alewood, Paul F.
, p. 13983 - 13986 (2012/01/06)
In the image: The design and synthesis of peptidomimetics that maintain the configuration of the triad Asp-Thr-Gly found in the catalytic site of the HIV-1 protease (see scheme) are described. By using regioselective nitration and reductive lactamisation,