198327-79-6

Basic information

• Product Name: (3-hydroxy-4-methoxy-2,6-dinitrophenyl)acetonitrile
• Synonyms: (3-hydroxy-4-methoxy-2,6-dinitrophenyl)acetonitrile
• CAS NO: 198327-79-6
• Molecular Weight: 253.171
• Mol File: 198327-79-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3-hydroxy-4-methoxy-2,6-dinitrophenyl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (3-hydroxy-4-methoxy-2,6-dinitrophenyl)acetonitrile(198327-79-6)
• EPA Substance Registry System: (3-hydroxy-4-methoxy-2,6-dinitrophenyl)acetonitrile(198327-79-6)

Safety Data

• Hazardous Substances Data: 198327-79-6(Hazardous Substances Data)

Upstream product

• 90-05-1 2-methoxy-phenol 
• 4097-63-6 2-methoxy-4,6-dinitrophenol 
• 3598-14-9 phenoxyacetonitrile 

Downstream Products

• 1361519-45-0 ethyl 3-(4-methoxy-2,6-dinitro-3-(trifluoromethylsulfonyloxy)phenyl)propanoate 
• 1361519-65-4 C₁₇H₁₄N₄O₇ 
• 1361519-64-3 2-(3-(benzyloxy)-4-methoxy-2,6-dinitrophenyl)acetic acid 
• 1361519-63-2 ethyl 3-(3-(benzyloxy)-4-methoxy-2,6-dinitrophenyl)propanoate 
• 1361519-62-1 ethyl 2-(3-(benzyloxy)-4-methoxy-2,6-dinitrophenyl)acetate 
• 1361519-44-9 ethyl 3-(4-methoxy-2,6-dinitro-3-((1-phenyl-1H-tetrazol-5-yl)oxy)phenyl)propanoate 
• 1361519-42-7 ethyl 3-(3-hydroxy-4-methoxy-2,6-dinitrophenyl)propanoate 
• 1361519-51-8 2-(5-((tert-butoxycarbonyl)amino)-7-((2,6-dichlorobenzyl)oxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid 
• 1361519-57-4 ethyl 2-(5-((tert-butoxycarbonyl)amino)-7-((2,6-dichlorobenzyl)oxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetate 
• 1361519-50-7 tert-butyl (7-((2,6-dichlorobenzyl)oxy)-2-oxo-1,2,3,4-tetrahydroquinolin-5-yl)carbamate 
• 1361519-61-0 ethyl 2-(3-hydroxy-4-methoxy-2,6-dinitrophenyl)acetate 
• 198327-80-9 3-Cyano-3-(3,4-dimethoxy-2,6-dinitro-phenyl)-propionic acid ethyl ester 
• 146495-41-2 (3,4-dimethoxy-2,6-dinitrophenyl)acetonitrile 

Relevant articles and documents

Synthesis of 7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline: A key intermediate en route to makaluvamines, discorhabdin C and other marine alkaloids of this group via vicarious nucleophilic substitution of hydrogen

The title compound 1a, a key intermediate in synthesis of an important group of alkaloids, is efficiently prepared via vicarious nucleophilic substitution of hydrogen followed by simple transformations.

On the synthesis of two dimethoxy-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline regioisomers

Many marine alkaloids are biologically active products and possess the 1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline core as a common feature. This is a report of the synthesis of two of the title molecules with confirmation of their structure.