1363739-56-3

Basic information

• Product Name: 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil
• Synonyms: 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil
• CAS NO: 1363739-56-3
• Molecular Weight: 570.67
• Mol File: 1363739-56-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil(1363739-56-3)
• EPA Substance Registry System: 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil(1363739-56-3)

Safety Data

• Hazardous Substances Data: 1363739-56-3(Hazardous Substances Data)

Upstream product

• 139887-97-1 2’,5’-dideoxy-3’-O-[(1,1-dimethylethyl)dimethylsilyl]-5’-oxouridine 
• 76223-05-7 1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 
• 1363739-50-7 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-bromouracil 
• 1765-93-1 4-fluoroboronic acid 
• 1363739-49-4 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]uracil 
• 1363739-44-9 1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hex-5-enofuranosyl]uracil 

Downstream Products

• 1363739-61-0 1-[2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil 
• 1363739-76-7 1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-α-D-hexofuranosyl]-5-(4-fluorophenyl)uracil 
• 1363739-73-4 1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil 

Relevant articles and documents

Synthesis of 5-substituted 2′-deoxyuridine-5′- phosphonate analogues and evaluation of their antiviral activity

A small series of 5-(hetero)aryl-modified nucleoside phosphonates was synthesized via an 8-step procedure including a Wittig reaction and Suzuki-Miyaura coupling. An unanticipated anomerization during phosphonate deprotection allowed us to isolate both anomers of the 5-substituted 2′-deoxy-uridine phosphonates and assess their antiviral activity against a broad panel of viruses. Copyright Taylor and Francis Group, LLC.