136466-94-9

Basic information

• Product Name: 2,6-Difluoropyridine-3-boronic acid
• Synonyms: (2,6-DIFLUORO-3-PYRIDINYL)-BORONIC ACID;2,6-DIFLUORO-3-PYRIDYL BORONIC ACID;(2,6-DIFLUOROPYRIDIN-3-YL)BORONIC ACID;2,6-DIFLUOROPYRIDINE-3-BORONIC ACID;Boronic acid, (2,6-difluoro-3-pyridinyl)- (9CI);6-Chloro-2-fluoropyridine-3-boronic acid;REF DUPL: 2,6-Difluoropyridine-3-boronic acid;2,6-Difluoro-3-pyridineboronic Acid (contains varying amounts of Anhydride)
• CAS NO: 136466-94-9
• Molecular Formula: C₅H₄BF₂NO₂
• Molecular Weight: 175.35
• Product Categories: HALIDE;Boronic Acids & Esters;Boronic Acids & Esters;Pyridines;Boronic Acid
• Mol File: 136466-94-9.mol
• Article Data: 13

Chemical Properties

• Melting Point: 168 °C(Solv: ethyl acetate (141-78-6); ethyl ether (60-29-7))
• Boiling Point: 314.8 °C at 760 mmHg
• Flash Point: 144.2 °C
• Appearance: White powder
• Density: 1.44 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.483
• Storage Temp.: Store Cold
• PKA: 6.77±0.58(Predicted)
• Water Solubility: Soluble in water
• CAS DataBase Reference: 2,6-Difluoropyridine-3-boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Difluoropyridine-3-boronic acid(136466-94-9)
• EPA Substance Registry System: 2,6-Difluoropyridine-3-boronic acid(136466-94-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37
• Hazardous Substances Data: 136466-94-9(Hazardous Substances Data)

Usage

General Description

2,6-Difluoropyridine-3-boronic acid is a chemical compound with the molecular formula C5H4B F2N2O2. It is a boronic acid derivative of 2,6-difluoropyridine, containing a boronic acid functional group attached to the 3-position of the pyridine ring. 2,6-Difluoropyridine-3-boronic acid has potential applications in organic synthesis and pharmaceutical research, as boronic acids are widely used as building blocks for the synthesis of various pharmaceuticals, agrochemicals, and materials. The 2,6-difluoropyridine-3-boronic acid may be used as a reagent in coupling reactions to form carbon-carbon and carbon-heteroatom bonds, as well as in the development of new drug candidates and biologically active molecules. Its properties and reactivity make it a valuable tool for chemical and pharmaceutical research.

InChI:InChI=1/C5H4BF2NO2/c7-4-2-1-3(6(10)11)5(8)9-4/h1-2,10-11H

Upstream product

• 1513-65-1 2,6-difluoro pyridine 
• 121-43-7 Trimethyl borate 
• 108-18-9 diisopropylamine 
• 7732-18-5 water 
• 5419-55-6 Triisopropyl borate 

Downstream Products

• 136466-93-8 2,6-difluoro-3-[4-(trans-4-pentylcyclohexyl)phenyl]-pyridine 
• 1000981-84-9 2,6-difluoro-3-(4'-nitrophenyl)pyridine 
• 1000981-83-8 2,6-difluoro-3-(4'-methoxyphenyl)pyridine 
• 1132811-16-5 C₂₆H₂₀F₄N₄ 
• 1132811-19-8 C₃₃H₂₀F₄N₄ 
• 1132811-31-4 C₃₅H₂₄F₄N₄O₂ 
• 1132811-33-6 C₃₉H₃₂F₄N₄O₂ 
• 1132811-35-8 C₂₈H₁₈F₄N₄ 
• 1606120-28-8 3-cyano-4-((2,6-difluoro-[3,2’: 4’,4’‘-terpyridin]-5’-yl)oxy)-N-(thiazol-2-yl)benzenesulfonamide 

Relevant articles and documents

Blue phosphorescent ir(III) complex with high color purity: Fac-tris(2′,6′-difluoro-2,3′-bipyridinato-N,C 4′)iridium(III)

A blue phosphorescent iridium(III) complex (1) bearing fluorine-substituted bipyridine (dfpypy) has been synthesized and characterized to investigate the effect of the substitution and replacement of the phenyl ring in ppy (phenylpyridine) with pyridine o

Blue phosphorescent bipyridine-based iridium(III) complex for vacuum-deposited organic light-emitting diodes

We have synthesized and characterized a blue phosphorescent iridium(III) complex (dfpypy)2Ir(tftamp), which contains 2,6-difluoro-2,3-bipyridine (dfpypy) as the main ligand and 4-methyl-2-(3-trifluoromethyl-1H-1,2,4-triazol-5-yl)pyridine (tftamp) as the ancillary ligand. The photophysical, electrochemical, and electroluminescent (EL) properties of (dfpypy)2Ir(tftamp) were investigated. Vacuum-deposited blue and white organic light-emitting diodes (OLEDs) were fabricated using (dfpypy)2Ir(tftamp) in 1,3-bis(carbazol-9-yl)benzene (mCP) as the emitting layer. The EL spectrum of (dfpypy)2Ir(tftamp) exhibited emission maximum at 472 nm with a full-width at half-maximum (FWHM) of 81 nm and Commission Internationale de L’Eclairage (CIE) coordinates of (0.17, 0.27) at 100 cd · m?2. In addition, white-light-emitting devices were fabricated, which exhibited CIE coordinates of (0.42, 0.40) and a correlated color temperature (CCT) of 3,237 K at 1000 cd · m?2, close to the standard warm-white light CIE coordinates of (0.44, 0.40) and CCT of 3,000 K.

Unusual dual-emissive heteroleptic iridium complexes incorporating TADF cyclometalating ligands

Five new neutral heteroleptic iridium(iii) complexes IrL2(pic) (2-6) based on the archetypical blue emitter FIrpic have been synthesised. The cyclometallating ligands L are derived from 2-(2,6-F2-3-pyridyl)-4-mesitylpyridine (7), 2-(