1369255-19-5Relevant articles and documents
PYRIMIDONE COMPOUNDS USED AS LP-PLA2 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS THEREOF
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Paragraph 0119; 0121; 0125, (2017/11/18)
The present invention relates to pyrimidone compounds used as Lp-PLA2 inhibitors and pharmaceutical compositions thereof. The structure of the pyrimidone compounds is represented by general formula (I), wherein R1, R2, Rs
BICYCLIC PYRIMIDONE COMPOUNDS AS INHIBITORS OF LP-PLA2
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Page/Page column 25; 42, (2014/08/07)
The present invention relates to novel pyrimido[1,6-a]pyrimidin-6(2H)-one compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.
TRICYCLIC COMPOUNDS, PREPARATION METHODS, AND THEIR USES
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Page/Page column 36-37, (2012/04/10)
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.