218301-22-5 Usage
Description
2-Fluoro-5-formylbenzonitrile is a benzonitrile derivative, characterized by its white solid appearance. It is a chemical compound that holds significant potential in various applications due to its unique structure and properties.
Uses
Used in Pharmaceutical Industry:
2-Fluoro-5-formylbenzonitrile is used as a key intermediate in the preparation of heterocyclic compounds, specifically as PARP inhibitors for medical use. These PARP inhibitors play a crucial role in the treatment of various types of cancer by targeting and disrupting the DNA repair mechanisms in cancer cells, thereby enhancing the effectiveness of chemotherapy and radiation therapy.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Fluoro-5-formylbenzonitrile may be utilized in the synthesis of 3-cyano-4-fluorobenzyl bromide. 2-FLUORO-5-FORMYLBENZONITRILE serves as an important building block for the development of various pharmaceuticals, agrochemicals, and other specialty chemicals, highlighting the versatility of 2-Fluoro-5-formylbenzonitrile in different chemical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 218301-22-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,3,0 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 218301-22:
(8*2)+(7*1)+(6*8)+(5*3)+(4*0)+(3*1)+(2*2)+(1*2)=95
95 % 10 = 5
So 218301-22-5 is a valid CAS Registry Number.
InChI:InChI=1S/C8H4FNO/c9-8-2-1-6(5-11)3-7(8)4-10/h1-3,5H
218301-22-5Relevant articles and documents
Novel indazole derivatives, and use thereof
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Paragraph 0112-0124, (2019/08/12)
The present invention refers to novel indazole derivatives, or pharmaceutically acceptable salts; and including DYRK1A DYRK1B active ingredient (Dual non-specificity tyrosine phosphorylation in a non-regulated kinase 1a) or a pharmaceutical composition for preventing or treating related disorders are disclosed. (by machine translation)
HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF
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Paragraph 0137; 0138, (2013/09/12)
Disclosed are heterocyclic derivatives, methods for making them, compositions containing the same and uses thereof. Particularly, their pharmaceutical use as inhibitors of PARP is disclosed.
NOVEL OXADIAZOLE COMPOUNDS
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Page/Page column 176-177, (2011/06/26)
Novel oxadiazole compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions as agonists or antagonists of the S1P family of G protein-coupled receptors for treating diseases associated with modulation o
