1370334-05-6

Basic information

• Product Name: 2-(4-bromophenyl)-6-difluoromethylpyrimidin-4-one
• Synonyms: 2-(4-bromophenyl)-6-difluoromethylpyrimidin-4-one
• CAS NO: 1370334-05-6
• Molecular Weight: 301.09
• Mol File: 1370334-05-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenyl)-6-difluoromethylpyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)-6-difluoromethylpyrimidin-4-one(1370334-05-6)
• EPA Substance Registry System: 2-(4-bromophenyl)-6-difluoromethylpyrimidin-4-one(1370334-05-6)

Safety Data

• Hazardous Substances Data: 1370334-05-6(Hazardous Substances Data)

Upstream product

• 55368-42-8 4-bromobenzamidine hydrochloride 
• 89129-66-8 4,4-difluoro-3-oxo-butanoic acid methyl ester 
• 623-00-7 4-bromobenzenecarbonitrile 

Downstream Products

• 1370334-08-9 2-(4-bromophenyl)-4-chloro-6-difluoromethylpyrimidine 
• 504400-22-0 2-{[2-(4-bromophenyl)-6-difluoromethylpyrimidin-4-yl]amino}ethanol 

Relevant articles and documents

Synthesis and structure-activity relationship of 4-amino-2-phenylpyrimidine derivatives as a series of novel GPR119 agonists

Through preparation and examination of a series of novel 4-amino-2-phenylpyrimidine derivatives as agonists for GPR119, we identified 2-(4-bromophenyl)-6-methyl-N-[2-(1-oxidopyridin-3-yl)ethyl]pyrimidin-4-amine (9t). Compound 9t improved glucose tolerance in mice following oral administration and showed good pharmacokinetic profiles in rats.