137117-06-7

Basic information

• Product Name: phenyl(2-phenylquinolin-4-yl)methanone
• Synonyms: phenyl(2-phenylquinolin-4-yl)methanone
• CAS NO: 137117-06-7
• Molecular Weight: 309.367
• Mol File: 137117-06-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: phenyl(2-phenylquinolin-4-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl(2-phenylquinolin-4-yl)methanone(137117-06-7)
• EPA Substance Registry System: phenyl(2-phenylquinolin-4-yl)methanone(137117-06-7)

Safety Data

• Hazardous Substances Data: 137117-06-7(Hazardous Substances Data)

Upstream product

• 59-48-3 2-oxoindole 
• 94-41-7 benzalacetophenone 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 612-96-4 2-Phenylquinoline 
• 260972-84-7 phenyl(2-phenylquinolin-4-yl)methanol 
• 4903-36-0 N-phenyl-benzimidoyl chloride 
• 57900-02-4 1-(1-(allyloxy)prop-2-ynyl)benzene 
• 137116-92-8 1,3,6-triphenyl-1,4,5,6-tetrahydropyridazine 
• 23686-03-5 1,3,6-triphenyl-1,4-dihydro-pyridazine 
• 137117-04-5 4-benzoyl-2-phenyl-1,2,3,4-tetrahydroquinoline 
• 59661-86-8 2-phenylquinoline-4-carbonyl chloride 

Downstream Products

• 26873-29-0 diphenyl-(2-phenyl-quinolin-4-yl)-methanol 

Relevant articles and documents

2-Oxindole Acts as a Synthon of 2-Aminobenzoyl Anion in the K2CO3-Catalyzed Reaction with Enones: Preparation of 1,4-Diketones Bearing an Amino Group and Their Further Transformations

A convenient approach for the synthesis of 1,4-diketones bearing an amino group has been developed through the K2CO3-catalyzed reaction of 2-oxindoles with enones with the assistance of atmospheric O2 via sequential Michael addition-oxidation-ring-cleavage process. The further intramolecular reaction leads to the formation of benzoazepinone, quinoline, and 3-oxindole derivatives.

Unexpected domino reaction via Pd-catalyzed Sonogashira coupling of benzimidoyl chlorides with 1,6-enynes and cyclization to synthesize quinoline derivatives

(Chemical Equation Presented) A domino reaction via palladium-catalyzed Sonogashira coupling of benzimidoyl chlorides with 1,6-enynes and then cyclization to form quinoline derivatives has been developed. The reaction conditions and the scope of the process are examined, and a plausible mechanism is proposed. The procedure is simple, rapid, and general, and the substrates are readily available. 2010 American Chemical Society.