13728-11-5 Usage
Description
[(4-chlorophenyl)(nitroso)amino]acetic acid, a chemical compound with the molecular formula C8H7ClN2O3, is a nitrosamine derivative characterized by the presence of a chlorophenyl group, a nitroso group, and an acetic acid moiety. [(4-chlorophenyl)(nitroso)amino]acetic acid is significant in both the pharmaceutical and environmental sectors due to its chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
[(4-chlorophenyl)(nitroso)amino]acetic acid is used as an organic synthesis intermediate for the production of pharmaceuticals. Its unique structure and functional groups make it a valuable component in the development of new drugs.
Used in Research and Development:
In the field of research and development, [(4-chlorophenyl)(nitroso)amino]acetic acid is utilized for studying its potential anti-inflammatory and anti-cancer properties. These studies aim to explore its therapeutic potential and contribute to the advancement of medical treatments.
Used in Environmental Monitoring:
As a known metabolic product of certain pesticides and a potential environmental pollutant, [(4-chlorophenyl)(nitroso)amino]acetic acid is used in environmental monitoring and assessment. Its detection and analysis help in understanding the impact of pesticide use on the environment and human health.
Check Digit Verification of cas no
The CAS Registry Mumber 13728-11-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,2 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13728-11:
(7*1)+(6*3)+(5*7)+(4*2)+(3*8)+(2*1)+(1*1)=95
95 % 10 = 5
So 13728-11-5 is a valid CAS Registry Number.
13728-11-5Relevant articles and documents
Novel sydnone derivatives carrying azidomethyl-1,2, 4-oxadiazole unit and their 1,3-dipolar cycloadditions
Dürüst, Ya?ar,Y?ld?z, Elif,Karaku?, Hamza,Kariuki, Benson M.
, p. 660 - 670 (2017/03/24)
A series of 1,2,4-oxadiazolymethyl sydnones carrying azido group were synthesized and subjected to react with a variety of alkenic and acetylenic dipolarophilic reagents; N-phenyl maleimide, phenyl vinyl sulfone, and phenyl propiolic acid. All the new products are identified by spectral/physical data including high-resolution mass measurements and X-ray diffraction data.
Synthesis of 2H-indazoles by the [3 + 2] cycloaddition of arynes and sydnones
Wu, Chunrui,Fang, Yuesi,Larock, Richard C.,Shi, Feng
supporting information; experimental part, p. 2234 - 2237 (2010/08/04)
A rapid and efficient synthesis of 2H-indazoles has been developed, which involves the [3 + 2] dipolar cycloaddition of arynes and sydnones. The process proceeds under mild reaction conditions in good to excellent yields.
Microwave-assisted synthesis of N-arylglycines: Improvement of sydnone synthesis
Azarifar, Davood,Bosra, Hassan Ghasemnejad,Zolfigol, Mohammad-Ali,Tajbaksh, Mahmood
, p. 175 - 181 (2007/10/03)
Reactions of anilines with ethyl bromoacetate under microwave irradiation have afforded N-arylglycines that are subsequently converted to their N-nitroso derivatives with a combination of silica chloride or periodic acid, wet SiO2 and sodium nitrite in CH2Cl2 with satisfactory yields. In the final step, the use of 1,3-dibromo-5,5-dimethylhydantoin (DBH) as a new and effective reagent for dehydration of N-nitroso-N-arylglycines to sydnones was successfully examined.
