137351-39-4

Basic information

• Product Name: 2-Butanone, 1-chloro-3,3-dimethyl-1-(phenylthio)-
• CAS NO: 137351-39-4
• Molecular Formula: C12H15ClOS
• Molecular Weight: 242.77
• Mol File: 137351-39-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 1-chloro-3,3-dimethyl-1-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 1-chloro-3,3-dimethyl-1-(phenylthio)-(137351-39-4)
• EPA Substance Registry System: 2-Butanone, 1-chloro-3,3-dimethyl-1-(phenylthio)-(137351-39-4)

Safety Data

• Hazardous Substances Data: 137351-39-4(Hazardous Substances Data)

Upstream product

• 75-97-8 3,3-dimethyl-butan-2-one 
• 5469-26-1 1-Bromopinacolon 
• 37471-41-3 3,3-dimethyl-1-(phenylthio)butan-2-one 

Downstream Products

• 137351-35-0 3,3-dimethyl β-keto α-thiophenyl butyl p-toluene sulfone 

Relevant articles and documents

Elaboration of 1-benzoyltetrahydroisoquinoline derivatives employing a Pictet-Spengler cyclization with α-chloro-α-phenylthioketones. Synthesis of O-methylvelucryptine

The reaction of N-tosyl-β-phenethylamines with α-chloro-α-phenylthioketones, leading to 1-benzoyl- and 1-pivaloyl-tetrahydroisoquinolines under modified Pictet-Spengler conditions, is described. The synthesis of O-methylvelucryptine employing this transformation as a key step is reported.