13757-08-9Relevant articles and documents
Regio- and stereoselectivity in the concatenated enyne cross metathesis-metallotropic [1,3]-shift of terminal 1,3-diyne This article is dedicated to Professor Paul A. Wender on the occasion of his receiving the 2012 Tetrahedron Prize for Creativity in Organic Chemistry
Wang, Kung-Pern,Cho, Eun Jin,Yun, Sang Young,Rhee, Jee Young,Lee, Daesung
supporting information, p. 9105 - 9110 (2013/09/24)
Enyne cross metathesis of terminal 1,3-diynes with various alkenes afforded two products of distinctive connectivity, as the result of a uniform mode of initiation but different modes of termination events with or without metallotropic [1,3]-shift. Steric and electronic factors of the substituents on the 1,3-diynes play an important role in controlling the metallotropic [1,3]-shift of the propagating alkylidene intermediates and their regioselective trapping to the final products.
Hydration of Diacetylene Compounds. Synthesis of a Marine Natural Product: (+/-)-1-(2,6,6-Trimethyl-4-hydroxycyclohexenyl)-1,3-butanedione
Constantino, Mauricio G.,Donate, Paulo M.,Petragnani, Nicola
, p. 387 - 390 (2007/10/02)
The marine natural product (+/-)-1-(2,6,6-trimethyl-4-hydroxycyclohexenyl)-1,3-butanedione (1) was synthesized from known the keto alcohol 3 and 1,4-dichlorobut-2-yne.The synthetic sequence involves dehydration of the diyne tertiary alcohol 2 and hydratio
