13810-02-1

Basic information

• Product Name: Cyclohexanecarboxamide, N-hydroxy-
• CAS NO: 13810-02-1
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.186
• Mol File: 13810-02-1.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxamide, N-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxamide, N-hydroxy-(13810-02-1)
• EPA Substance Registry System: Cyclohexanecarboxamide, N-hydroxy-(13810-02-1)

Safety Data

• Hazardous Substances Data: 13810-02-1(Hazardous Substances Data)

Upstream product

• 3289-28-9 ethyl cyclohexanecarboxylate 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 61274-13-3 succinimidyl cyclohexanecarboxylate 
• 60718-45-8 1-cyclohexanecarbonyl-1H-imidazole 
• 4715-11-1 cyclohexanecarbaldoxime 
• 98-89-5 Cyclohexanecarboxylic acid 
• 4630-82-4 methyl cyclohexylcarboxylate 

Downstream Products

• 1122-56-1 cyclohexylcarboxamide 
• 3218-02-8 cyclohexylmethylamine 
• 64125-04-8 3-cyclohexyl-5-methoxycarbonylmethyl-[1,4,2]dioxazole-5-carboxylic acid methyl ester 
• 133808-19-2 Cyclohexanecarboxylic acid (adamantane-1-carbonyloxy)-amide 
• 133808-37-4 N-[(S)-1-(Cyclohexanecarbonyl-aminooxycarbonyl)-3-methyl-butyl]-benzamide 
• 133808-39-6 N-[3-(Cyclohexanecarbonyl-aminooxy)-3-oxo-propyl]-benzamide 
• 133808-17-0 O-benzoyl-N-cyclohexanecarbonyl-hydroxylamine 
• 886-59-9 N-cyclohexyl-N'-phenylurea 
• 3173-53-3 Cyclohexyl isocyanate 
• 70243-23-1 N-cyclohexyl-1H-benzo[d][1,2,3]triazole-1-carboxamide 
• 18860-06-5 2-cyclohexyl-5-phenyloxazole 
• 7107-58-6 benzyl N-cyclohexylcarbamate 
• 108-91-8 cyclohexylamine 
• 2158-01-2 N-butyl-N'-cyclohexylurea 

Relevant articles and documents

P(III)-Assisted Electrochemical Access to Ureas via in situ Generation of Isocyanates from Hydroxamic Acids

An external oxidant-free protocol for the generation of isocyanates from hydroxamic acids assisted by trivalent phosphine under mild electrochemical conditions was reported. The process started with the anodic oxidation of hydroxamic acids, followed by reacting with phosphine to form corresponding alkoxyphosphoniums and subsequent rearrangement with the release of tri-substituted phosphine oxide as the driving force to give isocyanates, which were trapped by N-based nucleophiles to produce various ureas. This method provides a broadly applicable procedure to access isocyanate intermediates under mild electrochemical conditions.

Synthesis of sulfimides and N-Allyl-N-(thio)amides by Ru(II)catalyzed nitrene transfer reactions of N-acyloxyamides

The N-acyloxyamides were employed as effective N-acyl nitrene precursors in reactions with thioethers under the catalysis of a commercially available Ru(II) complex, from which a variety of sulfimides were synthesized efficiently and mildly. If an allyl group is contained in the thioether precursor, the [2,3]-sigmatropic rearrangement of the sulfimide occurs simultaneously and the N-allyl-N-(thio)amides were obtained as the final products. Preliminary mechanistic studies indicated that the Ru-nitrenoid species should be a key intermediate in the transformation.

Co(III)-Catalyzed C-H Amidation of Nitrogen-Containing Heterocycles with Dioxazolones under Mild Conditions

A cobalt(III)-catalyzed C-8 selective C-H amidation of quinoline N-oxide using dioxazolone as an amidating reagent under mild conditions is disclosed. The reaction proceeds efficiently with excellent functional group compatibility. The utility of the current method is demonstrated by gram scale synthesis of C-8 amide quinoline N-oxide and by converting this amidated product into functionalized quinolines. Furthermore, the developed catalytic method is also applicable for C-7 amidation of N-pyrimidylindolines and ortho-amidation of benzamides.