138207-66-6

Basic information

• Product Name: N^α,N^ε-bis(benzyloxycarbonyl)-D-lysinal
• Synonyms: N^α,N^ε-bis(benzyloxycarbonyl)-D-lysinal
• CAS NO: 138207-66-6
• Molecular Weight: 398.459
• Mol File: 138207-66-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N^α,N^ε-bis(benzyloxycarbonyl)-D-lysinal(CAS DataBase Reference)
• NIST Chemistry Reference: N^α,N^ε-bis(benzyloxycarbonyl)-D-lysinal(138207-66-6)
• EPA Substance Registry System: N^α,N^ε-bis(benzyloxycarbonyl)-D-lysinal(138207-66-6)

Safety Data

• Hazardous Substances Data: 138207-66-6(Hazardous Substances Data)

Upstream product

• 405-39-0 N,N'-di-[(phenylmethoxy)carbonyl]-L-lysine 
• 110690-36-3 L-Lysinol 
• 501-53-1 benzyl chloroformate 
• 83173-67-5 N_α,N_ξ-di-Cbz-L-lysine ethyl ester 
• 3844-53-9 L-lysine ethyl ester dihydrochloride 
• 21160-83-8 N_α,N_ε-bis(carbobenzyloxy)-L-lysine N-hydroxysuccinimide ester 
• 55592-84-2 Nε-Cbz-lysine 
• 137649-64-0 N,N-bis-Cbz-L-lysinol 

Downstream Products

• 137649-70-8 (5S,6R,7R,8S)-1,5,8,12-Tetrakis-6,7-dodecanediol 
• 184635-12-9 (S)-1-((S)-2,6-Bis-benzyloxycarbonylamino-hexyl)-pyrrolidine-2-carboxylic acid 
• 184634-93-3 (R)-1-((S)-2,6-Bis-benzyloxycarbonylamino-hexyl)-pyrrolidine-2-carboxylic acid 
• 137649-82-2 {4-[(4S,5R,4'S,5'R)-4'-(4-Benzyloxycarbonylamino-butyl)-2,2'-dioxo-3,3'-bis-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-[5,5']bioxazolidinyl-4-yl]-butyl}-carbamic acid benzyl ester 
• 1432584-78-5 (S,Z)-N-((S)-2,6-bis(((benzyloxy)carbonyl)amino)hexylidene)-1-(tert-butoxy)-1-oxopropan-2-amine oxide 
• 1432584-79-6 (S)-tert-butyl 2-((S)-2,6-bis(((benzyloxy)carbonyl)amino)hexanamido)propanoate 
• 84765-39-9 (S)-tert-butyl 2-formamidopropanoate 
• 138207-68-8 (2R,3S)-bis(N-benzyloxycarbonyl)-3,7-diamino-2-hydroxyheptanoic acid methyl ester 
• 138207-67-7 (2S,3S)-bis(N-benzyloxycarbonyl)-3,7-diamino-2-hydroxyheptanoic acid methyl ester 
• 1311399-83-3 C₂₅H₂₇N₃O₇ 
• 138207-73-5 (2R,3R)-bis(N-benzyloxycarbonyl)-3,7-diamino-2-hydroxyheptanoic acid methyl ester 
• 138207-74-6 (2S,3R)-bis(N-benzyloxycarbonyl)-3,7-diamino-2-hydroxyheptanoic acid methyl ester 

Relevant articles and documents

Rigid spiroethers targeting the decoding center of the bacterial ribosome

Continuing our efforts towards understanding the principles governing ribosomal recognition and function, we have synthesized and evaluated a series of diversely functionalized 5,6-, 6,6- and 7,6-spiroethers. These compounds successfully mimic natural aminoglycosides regarding their binding to the decoding center of the bacterial ribosome. Their potential to inhibit prokaryotic protein production in vitro along with their antibacterial potencies have also been examined.

Procedure for the oxidation of β-amino alcohols to α-amino aldehydes

A novel procedure for the mild oxidation of β-amino alcohols to α-amino aldehydes using commercially available manganese(IV) oxide is reported. There are several important advantages of the new method, such as high enantiopurity of the reaction and the absence of either over-oxidation or any reaction by-products during the process. A number of N-protected L-α-amino aldehydes was obtained. All new compounds were characterized by their NMR spectra and optical rotation data. Georg Thieme Verlag Stuttgart.

Pinacol cross coupling of 2-[N-(alkoxycarbonyl)amino] aldehydes and aliphatic aldehydes by [V2Cl3(THF)6]2[Zn2Cl 6]. Synthesis of syn,syn-3-[N-(alkoxycarbonyl)amino] 1,2-diols

Slow addition of 2-[N-(alkoxycarbonyl)amino] aldehydes to mixtures of [V2Cl3(THF)6]2[Zn2Cl 6] and aliphatic aldehydes gave syn,syn-3-[N-(alkoxycarbonyl)amino] 1,2-diols in good yield and high enantiomeric purity (>99:1). The alkyl group of the N-alkoxycarbonyl was shown to influence the yield: Me > allyl > Bn > t-Bu. Only the syn,syn diastereomer was observed (>20:1), except with N-Cbz-alaninal (10:1:1), O-benzyl-N-Cbz-serinal (7:1), and N-Cbz-prolinal (5:1 to 12:1). A new serinai derivative, N-Cbz-O-TBS-serinal, was cross coupled with n-pentadecanal to give a derivative of xylo-D-C18-phytosphingosine.