138421-80-4

Basic information

• Product Name: trans-(+/-)-3,4,4',5'-Tetrahydro-4'-(4-chlorophenyl)-spiropyrazol>-1-one
• CAS NO: 138421-80-4
• Molecular Weight: 310.783
• Mol File: 138421-80-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: trans-(+/-)-3,4,4',5'-Tetrahydro-4'-(4-chlorophenyl)-spiropyrazol>-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(+/-)-3,4,4',5'-Tetrahydro-4'-(4-chlorophenyl)-spiropyrazol>-1-one(138421-80-4)
• EPA Substance Registry System: trans-(+/-)-3,4,4',5'-Tetrahydro-4'-(4-chlorophenyl)-spiropyrazol>-1-one(138421-80-4)

Safety Data

• Hazardous Substances Data: 138421-80-4(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 49545-70-2 E-2-(4-chlorobenzylidene)-1-tetralone 
• 59082-35-8 (Z)-2-(4-Chlorobenzylidene)-1-tetralone 

Downstream Products

• 138421-99-5 Z-2-(α-methyl-4-chlorobenzylidene)-1-tetralone 
• 138421-90-6 E-2-(α-methyl-4-chlorobenzylidene)-1-tetralone 
• 138422-07-8 cis-2-(4-chlorophenyl-cyclopropyl)-1-tetralone 
• 138422-07-8 C₁₈H₁₅ClO 
• 140454-97-3 C₁₈H₁₅ClN₂O 

Relevant articles and documents

Reactions of aliphatic diazo compounds: VI. Reactions of diazomethane and ethyl diazoacetate with (E)-2-arylmethylene-1,2,3,4-tetrahydronaphthalen-1-ones

Diazomethane and ethyl diazoacetate add to (E)-2-arylmethylene-1,2,3,4- tetrahydronaphthalen-1-ones in a regio- and stereoselective fashion, yielding the corresponding 4'-aryl-1,2,3,4,4',5'-hexahydro-3'H-naphthalene-2-spiro-3'- pyrazol-1-ones. The products formed by addition of ethyl diazoacetate undergo isomerization into 4,5-dihydro-1H-pyrazole derivatives.