1384975-12-5

Basic information

• Product Name: (Z)-3-cyanomethylene-2,3,9,9a-tetrahydro-9-benzyl-2,2-dimethyl-1,3-oxazolo[3,2-a]-imidazo[4,5-b]pyridine
• Synonyms: (Z)-3-cyanomethylene-2,3,9,9a-tetrahydro-9-benzyl-2,2-dimethyl-1,3-oxazolo[3,2-a]-imidazo[4,5-b]pyridine
• CAS NO: 1384975-12-5
• Molecular Weight: 318.378
• Mol File: 1384975-12-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-3-cyanomethylene-2,3,9,9a-tetrahydro-9-benzyl-2,2-dimethyl-1,3-oxazolo[3,2-a]-imidazo[4,5-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-cyanomethylene-2,3,9,9a-tetrahydro-9-benzyl-2,2-dimethyl-1,3-oxazolo[3,2-a]-imidazo[4,5-b]pyridine(1384975-12-5)
• EPA Substance Registry System: (Z)-3-cyanomethylene-2,3,9,9a-tetrahydro-9-benzyl-2,2-dimethyl-1,3-oxazolo[3,2-a]-imidazo[4,5-b]pyridine(1384975-12-5)

Safety Data

• Hazardous Substances Data: 1384975-12-5(Hazardous Substances Data)

Upstream product

• 32837-87-9 3-hydroxy-3-methyl-1-cyano-1-butyne 
• 61532-32-9 3-(Phenylmethyl)-3H-imidazo<4,5-b>pyridine 

Downstream Products

• 1384975-17-0 (E)-N-(3-{[5-amino-2,2-dimethyl-3(2H)-furanyliden]amino}-2-pyridinyl)-N-benzylformamide 

Relevant articles and documents

Stereoselective annelation of 3-substituted imidazo[4,5-b]pyridines with cyanoacetylenic alcohols and domino rearrangement of the adducts

Imidazo[4,5-b]pyridines are readily annelated (45-50 °C, 24-30 h, MeCN) with cyanoacetylenic tertiary -αalcohols to give stereoselectively functionalized 1,3-oxazolo[3,2-a]imidazo[4,5-b]pyridines in 50-88% yields. The adducts undergo a facile stereoselective hydrolytic dominorearrangement to functionalized derivatives of 2,3-diaminopyridines. ARKAT-USA, Inc.