138647-50-4 Usage
Description
1(2H)-Pyridinecarboxylic acid, 4-(4-chlorophenyl)-3,6-dihydro-, 1,1-dimethylethyl ester, commonly known as Clonazepam, is a chemical compound with the molecular formula C18H20ClNO2. It belongs to the benzodiazepine class of drugs and is used for its calming effects on the brain by enhancing the effects of a neurotransmitter.
Uses
Used in Pharmaceutical Industry:
Clonazepam is used as a medication for the treatment of certain types of seizures, panic disorder, and movement disorder. It works by enhancing the effects of a neurotransmitter in the brain, providing a calming effect. It is available by prescription only and is usually taken orally as a tablet.
Used in Neurological Applications:
Clonazepam is employed as a treatment for various neurological conditions, including epilepsy and other seizure disorders. It helps to control the frequency and severity of seizures by stabilizing the electrical activity in the brain.
Used in Psychiatric Applications:
In the psychiatric field, Clonazepam is used to manage panic disorder, a condition characterized by sudden and repeated episodes of intense fear or worry. It helps to alleviate the symptoms by promoting a sense of calm and reducing anxiety.
Used in Movement Disorder Treatment:
Clonazepam is also used to treat movement disorders, such as Parkinson's disease, where it helps to reduce muscle stiffness, tremors, and other involuntary movements.
Precautions:
Clonazepam should be used with caution as it can be habit-forming and has the potential for abuse. Side effects may include drowsiness, dizziness, and difficulty with coordination. It is essential to follow the prescribed dosage and consult a healthcare professional before using Clonazepam.
Check Digit Verification of cas no
The CAS Registry Mumber 138647-50-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,6,4 and 7 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 138647-50:
(8*1)+(7*3)+(6*8)+(5*6)+(4*4)+(3*7)+(2*5)+(1*0)=154
154 % 10 = 4
So 138647-50-4 is a valid CAS Registry Number.
138647-50-4Relevant articles and documents
TRPML MODULATORS
-
Paragraph 0314, (2021/06/26)
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
Design, synthesis and evaluation of substituted piperidine based KCNQ openers as novel antiepileptic agents
Yang, Shaoning,Lu, Dingqiang,Ouyang, Pingkai
supporting information, p. 1731 - 1735 (2018/05/04)
Epilepsy is a kind of disease with complicated pathogenesis. KCNQ (Kv7) is a voltage dependent potassium channel that is mostly associated with epilepsy and thus becomes an important target in the treatment of epilepsy. In this paper, a series of substituted piperidine derivatives targeting KCNQ were designed and synthesized by using scaffold hopping and active substructure hybridization. Compounds were evaluated by fluorescence-based thallium influx assay, Rb+ flow assay and electrophysiological patch-clamp assay. Results showed that some compounds possessed more potent potassium channel opening activity than Retigabine. More significantly, compound 11 was found to have good pharmacokinetic profiles in vivo.
METALLO-BETA-LACTAMASE INHIBITORS
-
Paragraph 0784, (2016/12/01)
The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.