1388021-46-2 Usage
Description
C23H28F2N4O3, also known as Paliperidone E-oxime, is an impurity of Paliperidone (P141000), which is an orally active antipsychotic agent. It is a chemical compound with a molecular structure consisting of 23 carbon atoms, 28 hydrogen atoms, 2 fluorine atoms, 4 nitrogen atoms, and 3 oxygen atoms.
Uses
1. Used in Pharmaceutical Industry:
C23H28F2N4O3 is used as an impurity in the production of Paliperidone, an antipsychotic agent. Its presence is significant for the pharmaceutical industry as it can affect the quality, efficacy, and safety of the final drug product. The industry aims to minimize the presence of this impurity to ensure the optimal performance and safety of Paliperidone as a treatment for various psychiatric disorders.
2. Used in Research and Development:
In the field of research and development, C23H28F2N4O3 can be used as a subject of study to understand the properties, behavior, and potential applications of this specific compound. Researchers may investigate its chemical interactions, stability, and possible uses in various applications, including drug development and other industrial processes.
3. Used in Quality Control and Analysis:
C23H28F2N4O3 is also used in quality control and analysis within the pharmaceutical industry. Analyzing and monitoring the levels of this impurity in the final drug product helps ensure that the product meets the required safety and efficacy standards. This is crucial for maintaining the trust of healthcare professionals and patients in the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 1388021-46-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,8,0,2 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1388021-46:
(9*1)+(8*3)+(7*8)+(6*8)+(5*0)+(4*2)+(3*1)+(2*4)+(1*6)=162
162 % 10 = 2
So 1388021-46-2 is a valid CAS Registry Number.
1388021-46-2Relevant articles and documents
Preparation method of palipefidone
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Paragraph 0067; 0068; 0069; 0070; 0071, (2016/10/10)
The invention provides a preparation method of palipefidone. The preparation method comprises the following steps: dissolving a palipefidone crude product into a heated alcohol solution; adding active carbon under a heating condition; keeping heat and stirring; filtering when the solution is hot to obtain a filtrate; at a temperature of 45 DEG C to 60 DEG C, adding a reducing agent into the filtrate, and keeping the heat and stirring for 30 to 60 minutes; after stirring, controlling to cool for 8 DEG C to 15 DEG C every hour; slowly cooling and crystallizing; after crystallizing, filtering to obtain a solid and a refined mother solution respectively; performing water washing, alcohol washing and vacuum drying on the obtained solid to obtain palipefidone crystallized powder; decompressing and concentrating the refined mother solution and recycling palipefidone secondary precipitate. The preparation method of the palipefidone is simple in process and convenient to operate, does not need special equipment and is suitable for industrial production; a toxin-free or low-toxin solvent is adopted, so that environmental pollution is lowered; the prepared product has high purity, and the content of 9-keto impurities is reduced to be 0.05 percent, even lower.
Processes for the Preparation of Paliperidone and Pharmaceutically Acceptable Salts Thereof and Intermediates for Use in the Processes
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Page/Page column 14, (2010/12/29)
The present invention relates to novel compounds of formula (VIII) and (X), processes for their preparation and their use in the preparation of paliperidone or a salt thereof. There is also provided by the present invention novel processes for preparing intermediates for use in the preparation of paliperidone or a salt thereof, and novel processes for preparing paliperidone or a salt thereof.
