1388149-36-7Relevant articles and documents
METHODS AND COMPOUNDS USEFUL IN SYNTHESIS OF FUSED AMINO-DIHYDROTHIAZINE DERIVATIVES
-
Paragraph 0213, (2018/09/02)
PROBLEM TO BE SOLVED: To provide compounds and methods useful for the preparation of compounds useful as inhibitors of β-site amyloid precursor protein (APP)-cleaving enzyme. SOLUTION: Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of β-site amyloid precursor protein (APP)-cleaving enzyme. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
FUSED AMINODIHYDROTHIAZINE DERIVATIVES USEFUL AS BACE INHIBITORS
-
, (2012/08/07)
The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine; A is CH or N; Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or -C≡N; and pharmaceutically acceptable salts thereof; which compound has an Αβ production inhibitory effect or a BACEl inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Αβ and typified by Alzheimer-type dementia.