1388149-37-8

Basic information

• Product Name: C₂₄H₂₅F₄N₅O₅S
• Synonyms: C₂₄H₂₅F₄N₅O₅S
• CAS NO: 1388149-37-8
• Molecular Weight: 571.553
• Mol File: 1388149-37-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₅F₄N₅O₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₅F₄N₅O₅S(1388149-37-8)
• EPA Substance Registry System: C₂₄H₂₅F₄N₅O₅S(1388149-37-8)

Safety Data

• Hazardous Substances Data: 1388149-37-8(Hazardous Substances Data)

Upstream product

• 1388149-60-7 1-(2-fluorophenyl)-2-((1,1,1-trifluorobut-3-en-2-yl)oxy)ethanone oxime 
• 1388149-66-3 N-((4aS,5S,7aS)-7a-(2-fluorophenyl)-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl)amine 
• 1388149-64-1 ((2S,3R,4S)-4-amino-4-(2-fluorophenyl)-2-(trifluoromethyl)tetrahydrofuran-3-yl)methanol (2S,3S)-2,3-bis(benzoyloxy)succinic acid 
• 1388149-61-8 1-(2-fluorophenyl)-2-((1,1,1-trifluorobut-3-en-2-yl)oxy)ethanone 
• 1388149-59-4 N-methoxy-N-methyl-2-(( 1,1,1-trifluorobut-3-en-2-yl)oxy)acetamide 
• 1388149-58-3 tert-butyl 2-((1,1 ,1-trifluorobut-3-en-2-yl)oxy)acetate 
• 1388149-23-2 tert-butyl ((4aS,5S,7aS)-7a-(2-fluoro-5-nitrophenyl)-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl)carbamate 
• 1388149-22-1 N-((4aS,5S,7aS)-7a-(2-fluoro-5-nitrophenyl)-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl)amine 
• 1388149-21-0 N-((4aS,5S,7aS)-7a-(2-fluorophenyl)-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl)benzamide 
• 1262803-54-2 N-(((3S,4R,5S)-3-(2-fluorophenyl)-4-(hydroxymethyl)-5-(trifluoromethyl)-tetrahydrofuran-3-yl)carbamothioyl)benzamide 
• 1262799-42-7 ((2S,3R,4S)-4-amino-4-(2-fluorophenyl)-2-(trifluoromethyl)tetrahydrofuran-3-yl)methanol 
• 1262799-41-6 (3aR,4S,6aS)-6a-(2-fluorophenyl)-4-(trifluoromethyl)hexahydrofuro[3,4-c]isoxazole 
• 1262799-40-5 (S)-1-(2-fluorophenyl)-2-((1,1,1-trifluorobut-3-en-2-yl)oxy)ethanone oxime 
• 1262799-38-1 (S)-N-methoxy-N-methyl-2-(( 1,1,1-trifluorobut-3-en-2-yl)oxy)acetamide 

Downstream Products

• 1388149-36-7 N-(3-((4aS,5S,7aS)-2-amino-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide 

Relevant articles and documents

FUSED AMINODIHYDROTHIAZINE DERIVATIVES

The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine;A is CH or N;Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or —C≡N; and pharmaceutically acceptable salts thereof; which compound has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.