1391745-10-0 Usage
Uses
Used in Pharmaceutical Industry:
(3aR-trans)-5-Chloro-2,3,3a,12b-tetrahydro-2-Methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole-13C,d3 β-D-Glucopyranosiduronic Acid is used as a metabolite in the pharmaceutical industry for the study and development of drugs, specifically for Asenapine (A788000). Its role as a metabolite helps in understanding the pharmacokinetics, efficacy, and safety profile of the parent drug, Asenapine.
Used in Research and Development:
In the field of research and development, this compound serves as a valuable tool for studying the metabolic pathways and interactions of Asenapine. It can be used to investigate the biotransformation processes, identify potential drug-drug interactions, and assess the impact of genetic variations on drug metabolism.
Used in Quality Control and Standardization:
(3aR-trans)-5-Chloro-2,3,3a,12b-tetrahydro-2-Methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole-13C,d3 β-D-Glucopyranosiduronic Acid can be employed as a reference material for quality control and standardization in the pharmaceutical industry. It helps ensure the consistency, purity, and potency of Asenapine-containing products by providing a benchmark for comparison and analysis.
Used in Drug Metabolism Studies:
(3aR-trans)-5-Chloro-2,3,3a,12b-tetrahydro-2-Methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole-13C,d3 β-D-Glucopyranosiduronic Acid is used as a substrate in drug metabolism studies to understand how Asenapine is metabolized in the body. It can provide insights into the enzymes involved in the metabolic process, the formation of active or inactive metabolites, and the potential impact on the overall pharmacological effect of the drug.
Check Digit Verification of cas no
The CAS Registry Mumber 1391745-10-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,1,7,4 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1391745-10:
(9*1)+(8*3)+(7*9)+(6*1)+(5*7)+(4*4)+(3*5)+(2*1)+(1*0)=170
170 % 10 = 0
So 1391745-10-0 is a valid CAS Registry Number.
1391745-10-0Relevant articles and documents
Synthesis of stable isotope-labeled metabolites of asenapine
Kuethe, Jeffrey T.
, p. 180 - 185 (2012/07/31)
The stable isotope-labeled synthesis of four of the major metabolites of asenapine is described. The synthesis of [13CD3]-asenapine N-oxide proceeded in two synthetic steps. Preparation of [13CD 3]-asenapine 11-