139177-61-0

Basic information

• Product Name: 5-Pyrimidinemethanol, 1,3-dicyclohexylhexahydro-5-nitro-
• CAS NO: 139177-61-0
• Molecular Formula: C17H31N3O3
• Molecular Weight: 325.451
• Mol File: 139177-61-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinemethanol, 1,3-dicyclohexylhexahydro-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinemethanol, 1,3-dicyclohexylhexahydro-5-nitro-(139177-61-0)
• EPA Substance Registry System: 5-Pyrimidinemethanol, 1,3-dicyclohexylhexahydro-5-nitro-(139177-61-0)

Safety Data

• Hazardous Substances Data: 139177-61-0(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 1794-90-7 2-nitropropane-1,3-diol 
• 108-91-8 cyclohexylamine 
• 126-11-4 2-hydroxymethyl-2-nitro-propane-1,3-diol 

Downstream Products

• 139157-70-3 1,3-dicyclohexyl 5-nitro 5-p-nitrobenzyl hexahydropyrimidine 
• 139157-71-4 1-methyl 2-(1,3-dicyclohexyl hexahydropyrimidine 5-ylidenemethyl) 5-nitroimidazole 
• 139157-72-5 1,3-dicyclohexyl 5-p-nitrobenzylidene hexahydropyrimidine 

Relevant articles and documents

Preparation and antiparasitic activity of new imidazoles bearing dioxane or hexahydropyrimidine moiety

5-Nitro-1,3-dioxane and 5-nitrohexahydropyrimidine salts are found to be suitable nucleophiles for S(RN)1 reactions. From C-alkylation products, base-promoted nitrous acid elimination and acid-catalyzed cleavage of the resulting acetals afford new compounds. Only the imidazole derivatives exhibit significant amoebicide and trichomonacide activities. Structure-activity relationships are discussed.