139263-23-3

Basic information

• Product Name: Benzenepropanoic acid, a-[(acetylthio)methyl]-2-methyl-
• CAS NO: 139263-23-3
• Molecular Formula: C13H16O3S
• Molecular Weight: 252.334
• Mol File: 139263-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-[(acetylthio)methyl]-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-[(acetylthio)methyl]-2-methyl-(139263-23-3)
• EPA Substance Registry System: Benzenepropanoic acid, a-[(acetylthio)methyl]-2-methyl-(139263-23-3)

Safety Data

• Hazardous Substances Data: 139263-23-3(Hazardous Substances Data)

Upstream product

• 156757-36-7 2-methyl-α-methylenebenzenepropanoic acid 
• 507-09-5 tiolacetic acid 

Downstream Products

• 145841-10-7 (S)-2-((R)-2-Acetylsulfanylmethyl-3-o-tolyl-propionylamino)-4-methylsulfanyl-butyric acid ethyl ester 
• 136511-43-8 Sch 42495 

Relevant articles and documents

Mercaptoacyl amino acid inhibitors of atriopeptidase. 1. Structure- activity relationship studies of methionine and S-alkylcysteine derivatives

A broad series of N-(3-mercaptoacyl) amino acid derivatives was evaluated for their ability to inhibit atriopeptidase (neutral endopeptidase, EC 3.4.24.11) in vitro and in vivo. Structural parameters studied were (i) the substituent on the 2-position of the 3-mercaptopropionyl moiety, (ii) the amino acid component, (iii) the S-terminal derivative, and (iv) the C- terminal derivative. Optimum activity was observed for derivatives of methionine and S-alkylcysteines. N-[3-Mercapto-2(S)-[(2- methylphenyl)methyl]-1-oxopropyl]-L-methionine was identified as a highly effective inhibitor of atriopeptidase meriting evaluation as a potential cardiovascular therapeutic agent.