145841-10-7

Basic information

• Product Name: L-Methionine, N-[2-[(acetylthio)methyl]-3-(2-methylphenyl)-1-oxopropyl]-, ethyl ester
• CAS NO: 145841-10-7
• Molecular Formula: C20H29NO4S2
• Mol File: 145841-10-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Methionine, N-[2-[(acetylthio)methyl]-3-(2-methylphenyl)-1-oxopropyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Methionine, N-[2-[(acetylthio)methyl]-3-(2-methylphenyl)-1-oxopropyl]-, ethyl ester(145841-10-7)
• EPA Substance Registry System: L-Methionine, N-[2-[(acetylthio)methyl]-3-(2-methylphenyl)-1-oxopropyl]-, ethyl ester(145841-10-7)

Safety Data

• Hazardous Substances Data: 145841-10-7(Hazardous Substances Data)

Upstream product

• 2899-36-7 L-methionine ethyl ester monohydrochloride 
• 139263-23-3 2(S)-acetylthiomethyl-3-(2-methylphenyl)propionic acid 
• 156757-36-7 2-methyl-α-methylenebenzenepropanoic acid 

Relevant articles and documents

Mercaptoacyl amino acid inhibitors of atriopeptidase. 1. Structure- activity relationship studies of methionine and S-alkylcysteine derivatives

A broad series of N-(3-mercaptoacyl) amino acid derivatives was evaluated for their ability to inhibit atriopeptidase (neutral endopeptidase, EC 3.4.24.11) in vitro and in vivo. Structural parameters studied were (i) the substituent on the 2-position of the 3-mercaptopropionyl moiety, (ii) the amino acid component, (iii) the S-terminal derivative, and (iv) the C- terminal derivative. Optimum activity was observed for derivatives of methionine and S-alkylcysteines. N-[3-Mercapto-2(S)-[(2- methylphenyl)methyl]-1-oxopropyl]-L-methionine was identified as a highly effective inhibitor of atriopeptidase meriting evaluation as a potential cardiovascular therapeutic agent.