1393935-90-4Relevant articles and documents
Divergent total synthesis of the natural antimalarial marinoquinolines A, B, C, e and unnatural analogues
Schwalm, Cristiane Storck,Correia, Carlos Roque D.
, p. 4836 - 4840 (2012/09/07)
A new synthetic route to marinoquinolines was developed, allowing the synthesis of several structurally related compounds from a common key intermediate. Four natural marinoquinolines (A, B, C and E) and nine unnatural new analogues were prepared by this strategy, which features a Heck-Matsuda reaction in pure water and the Pictet-Spengler reaction as key steps.