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13991-72-5

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13991-72-5 Usage

Description

1-(2-chloroethyl)-3-(3-methylcyclohexyl)-1-nitrosourea, also known as MeCCNU, is a chemotherapeutic agent derived from the nitrosourea class. It is characterized by its ability to cross the blood-brain barrier and damage the DNA of cancer cells, leading to cell death. MeCCNU possesses potent anticancer properties, making it a valuable pharmaceutical candidate for the treatment of various malignancies.

Uses

Used in Anticancer Applications:
MeCCNU is used as a chemotherapeutic agent for the treatment of various types of cancer, including brain tumors and Hodgkin's disease. Its ability to cross the blood-brain barrier and damage cancer cell DNA makes it particularly effective against these malignancies. However, its use is accompanied by serious side effects such as bone marrow suppression, liver toxicity, and an increased risk of secondary cancers, necessitating close patient monitoring during treatment.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, MeCCNU is used as an active ingredient in the development of cancer treatment drugs. Its unique properties, such as the ability to cross the blood-brain barrier and its potent DNA-damaging effects, make it a valuable component in the fight against cancer. However, due to its potential toxicity, the development and administration of MeCCNU-based drugs require careful consideration and stringent safety measures to minimize side effects and ensure patient safety.

Check Digit Verification of cas no

The CAS Registry Mumber 13991-72-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,9 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13991-72:
(7*1)+(6*3)+(5*9)+(4*9)+(3*1)+(2*7)+(1*2)=125
125 % 10 = 5
So 13991-72-5 is a valid CAS Registry Number.

13991-72-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-(3-methylcyclohexyl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names 1-(2-chloroethyl)-1-nitroso-3-(3-methylcyclohexyl)urea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13991-72-5 SDS

13991-72-5Downstream Products

13991-72-5Relevant articles and documents

The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives.

Johnston,McCaleb,Opliger,Montgomery

, p. 892 - 911 (2007/10/05)

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