1399843-67-4

Basic information

• Product Name: C₃₂H₅₀O₃
• CAS NO: 1399843-67-4
• Molecular Weight: 482.747
• Mol File: 1399843-67-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₂H₅₀O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₅₀O₃(1399843-67-4)
• EPA Substance Registry System: C₃₂H₅₀O₃(1399843-67-4)

Safety Data

• Hazardous Substances Data: 1399843-67-4(Hazardous Substances Data)

Upstream product

• 1399843-70-9 C₂₆H₃₄O₂ 
• 909566-59-2 N-methyl 3β-hydroxyandrost-5-ene-17β-carboxamide 
• 1778-02-5 Pregnenolone acetate 
• 15173-68-9 etienic acid 

Relevant articles and documents

Novel oxysterols activate the Hedgehog pathway and induce osteogenesis

Localized induction of bone formation is essential during orthopedic procedures that involve skeletal repair, such as surgical treatment of non-union bone fractures and degenerative disk disease. Herein we disclose the synthesis and biological evaluation of novel oxysterol derivatives designed as anabolic bone growth agents. Structure-activity relationship studies of oxysterol 4 have identified analogues such as 18, 21 and 30. These new analogues are characterized by higher potency in an osteoblast differentiation assay and/or by increased metabolic stability in human liver microsomes. Oxysterols 4, 18 and 21 were evaluated in vivo in a rat spinal fusion model.