140-08-9

Basic information

• Product Name: TRIS(2-CHLOROETHYL) PHOSPHITE
• Synonyms: 2-chloroethanolphosphite(3:1);2-chloro-ethanophosphite(3:1);Ethanol,2-chloro-,phosphite(3:1);tris(2-chloroethyl)esterofphosphorusacid;tris(beta-chloroethyl)phosphite;tris(chloroethyl)phosphite;PHOSPHOROUS ACID TRIS(2-CHLOROETHYL) ESTER;TRI-2-CHLOROETHYL PHOSPHITE
• CAS NO: 140-08-9
• Molecular Formula: C₆H₁₂Cl₃O₃P
• Molecular Weight: 269.49
• EINECS: 205-397-6
• Product Categories: Organics;Organic Building Blocks;Organic Phosphates/Phosphites;Phosphorus Compounds
• Mol File: 140-08-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 112-115 °C2 mm Hg(lit.)
• Flash Point: 375 °F
• Appearance: /
• Density: 1.328 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00359mmHg at 25°C
• Refractive Index: n20/D 1.487(lit.)
• Storage Temp.: -20°C
• CAS DataBase Reference: TRIS(2-CHLOROETHYL) PHOSPHITE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIS(2-CHLOROETHYL) PHOSPHITE(140-08-9)
• EPA Substance Registry System: TRIS(2-CHLOROETHYL) PHOSPHITE(140-08-9)

Safety Data

• Hazard Codes: T
• Statements: 45-21-25-36/37/38-23/24/25-46
• Safety Statements: 53-26-36/37/39-45-36/37
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• RTECS: KK2810000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 140-08-9(Hazardous Substances Data)

Usage

Description

TRIS(2-CHLOROETHYL) PHOSPHITE is a colorless liquid with a characteristic odor. It is miscible with most common organic solvents but insoluble in water, where it hydrolyzes. The compound undergoes intramolecular isomerization at higher temperatures, and it is advisable to minimize its exposure to air. TRIS(2-CHLOROETHYL) PHOSPHITE is also combustible.

Uses

Used in Chemical Synthesis:
TRIS(2-CHLOROETHYL) PHOSPHITE is used as a reagent in the chemical synthesis industry for its ability to react with various organic compounds due to its phosphite functional group. Its solubility in organic solvents makes it a versatile component in the synthesis of different chemical products.
Used in Flame Retardants:
In the plastics and polymer industry, TRIS(2-CHLOROETHYL) PHOSPHITE is used as an additive to enhance the flame retardancy of materials. Its combustible nature allows it to be used in formulations that improve the fire resistance of plastics and polymers, making them safer for various applications.
Used in Pharmaceutical Intermediates:
TRIS(2-CHLOROETHYL) PHOSPHITE serves as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical properties enable it to be a key component in the development of new medications, contributing to the advancement of medical treatments.
Used in Agrochemicals:
In the agrochemical industry, TRIS(2-CHLOROETHYL) PHOSPHITE is used as a component in the development of pesticides and other agricultural chemicals. Its reactivity with organic compounds makes it a valuable asset in creating effective products for crop protection and management.
Used in Research and Development:
TRIS(2-CHLOROETHYL) PHOSPHITE is utilized in research and development laboratories for its potential applications in various fields. Its unique properties and reactivity make it an interesting compound for scientists to study and explore its possible uses in creating new materials, chemicals, and pharmaceuticals.

Air & Water Reactions

Unstable to heat, moisture and prolonged exposure to air. Decomposes in water.

Reactivity Profile

TRIS(2-CHLOROETHYL) PHOSPHITE is unstable to heat, moisture and prolonged exposure to air. Hydrolyzes in water. Reacts vigorously with oxidizing agents. Undergoes vigorous isomerization .

InChI:InChI=1/C6H12Cl3O3P/c7-1-4-10-13(11-5-2-8)12-6-3-9/h1-6H2

Upstream product

• 75-21-8 oxirane 
• 110-86-1 pyridine 
• 60-29-7 diethyl ether 
• 7623-05-4 dichloro-(2-chloroethoxy)-phosphine 
• 64-17-5 ethanol 
• 107-07-3 2-chloro-ethanol 
• 37984-64-8 bis(β-chloroethyl) chlorophosphite 
• 19449-26-4 N,N-dimethylformamide ethylene acetal 
• 7719-12-2 phosphorus trichloride 

Downstream Products

• 108484-86-2 {[bis-(2-chloro-ethoxy)-phosphoryl]-methyl}-(dimethoxyphosphoryl-methyl)-disulfide 
• 122316-78-3 bis-[bis-(2-chloro-ethoxy)-phosphoryl-methyl]-disulfide 
• 1070-42-4 di(2-chloroethyl)phosphite 
• 6087-94-1 bis(2-chloroethyl) chlorophosphate 
• 3040-56-0 bis(2-chloroethyl) phosphate 
• 115-96-8 Tris(2-chloroethyl) phosphate 
• 6294-34-4 bis(2-chloroethyl) 2-chloroethylphosphonate 
• 5266-08-0 (2,2-Dichlor-vinyl)-bis-(2-chlorethyl)-phosphat 
• 2799-58-8 bis(2-chloroethyl) methylphosphonate 
• 62516-49-8 phosphoric acid-(2-chloro-ethyl ester)-diphenyl ester 
• 16278-48-1 phosphorous acid 1-[bis-(2-chloro-ethoxy)-phosphoryl]-2-ethyl-hexyl ester bis-(2-chloro-ethyl) ester 
• 16226-13-4 [1-(4-chloromethyl-[1,3,2]dioxaphospholan-2-yloxy)-2-ethyl-hexyl]-phosphonic acid bis-(2-chloro-ethyl) ester 
• 5630-71-7 2-chloroethyl diethyl phosphate 
• 23055-16-5 Trichlormethylphosphonsaeure-bis-(2-chlor-ethylester) 

Relevant articles and documents

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Method of preparing tris-(2-chloroethyl)phosphite

The present disclosure discloses a method of preparing tris-(2-chloroethyl)phosphite, comprising: continuously pumping phosphorus trichloride and ethylene oxide into a tubular pre-mixer for pre-mixing, respectively, and starting a refrigerant cooling unit of the microchannel reaction device simultaneously, to obtain a product tris-(2-chloroethyl)phosphite after complete reaction. The method according to the present disclosure not only significantly improves the content of the esterification product, thus increasing the production efficiency by 10 to 100 times than that of an ordinary tank reactor, but also reduces the residence time of the esterification product in the reactor from 110 hours to several minutes.