3040-56-0 Usage
Description
Bis(2-chloroethyl) hydrogen phosphate, also known as Di-β,β'-Chloroethylphosphoric Acid, is a dialkyl hydrogen phosphate compound. It is characterized by its ability to undergo electrophilic trifluoromethylation, which allows for the production of trifluoromethyl phosphates. This process enhances the lipophilicity of functional groups, making it a versatile compound in various applications.
Uses
Used in Pharmaceutical Industry:
Bis(2-chloroethyl) hydrogen phosphate is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its ability to increase the lipophilicity of functional groups through electrophilic trifluoromethylation makes it a valuable component in the development of new drugs with improved properties.
Used in Chemical Synthesis:
In the field of chemical synthesis, bis(2-chloroethyl) hydrogen phosphate is utilized as a reagent to produce trifluoromethyl phosphates. These compounds are important in the creation of various chemical products, including those with enhanced lipophilic properties, which can be beneficial in a range of applications, such as increasing the solubility and bioavailability of certain substances.
Used in Research and Development:
Bis(2-chloroethyl) hydrogen phosphate is also employed in research and development settings, where its unique properties are explored for potential applications in creating new materials, improving existing compounds, and understanding the underlying chemical reactions involved in its synthesis and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 3040-56-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,4 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3040-56:
(6*3)+(5*0)+(4*4)+(3*0)+(2*5)+(1*6)=50
50 % 10 = 0
So 3040-56-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H9Cl2O4P/c5-1-3-9-11(7,8)10-4-2-6/h1-4H2,(H,7,8)
3040-56-0Relevant articles and documents
Reactivity of an electrophilic hypervalent iodine trifluoromethylation reagent with hydrogen phosphates - A mechanistic study
Santschi, Nico,Geissbühler, Patrik,Togni, Antonio
experimental part, p. 83 - 86 (2012/03/27)
The electrophilic trifluoromethylation of hydrogen phosphates with the reagent trifluoromethyl-1,3-dihydro-3,3-dimethyl-1,2-benziodoxole (1) was studied by means of initial rates determined for pseudo first order setups and subsequent Taft analysis of the calculated relative rates. A positive polar sensitivity factor, indicative of a negative charge forming during the rate-determining step, was found for the whole data set.
