14019-66-0 Usage
Description
(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester is an Uncaria alkaloid, which is a type of organic compound derived from the plant genus Uncaria. This specific alkaloid forms a colorless, non-crystallizable glass with a specific rotation of [α]D + 84° (CHCI3). It is stereoisomeric with other alkaloids of the same species, meaning it shares the same molecular formula but has a different arrangement of atoms in space.
Uses
Used in Pharmaceutical Industry:
(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester is used as a pharmaceutical compound for its potential therapeutic applications. Its unique structure and stereoisomeric properties make it a promising candidate for the development of new drugs targeting various health conditions.
Used in Research and Development:
In the field of research and development, (3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester serves as a valuable compound for studying the properties and interactions of stereoisomers. This can lead to a better understanding of their potential applications in various industries, including pharmaceuticals, agriculture, and materials science.
Used in Chemical Synthesis:
(3R,20S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester can be used as a starting material or intermediate in the synthesis of other complex organic compounds. Its unique structure and functional groups make it a versatile building block for creating new molecules with specific properties and applications.
References
Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., J. Pharm. Pharmacol., 24, 169P (1972)
Circular dichroism:
Beecham et al., Tetrahedron Lett., 991 (1967)
Check Digit Verification of cas no
The CAS Registry Mumber 14019-66-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,0,1 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 14019-66:
(7*1)+(6*4)+(5*0)+(4*1)+(3*9)+(2*6)+(1*6)=80
80 % 10 = 0
So 14019-66-0 is a valid CAS Registry Number.
InChI:InChI=1/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13+,14-,18-,21-/m1/s1
14019-66-0Relevant articles and documents
Analysis of the kinetics of isomerization of spiro oxindole alkaloids
Laus, Gerhard,Broessner, Dagmar,Senn, Gilbert,Wurst, Klaus
, p. 1931 - 1936 (1996)
The isomerization of the spiro oxindole alkaloids mitraphylline, isomitraphylline, pteropodine, isopteropodine, speciophylline and uncarine F in water has been studied at several temperatures and the rate coefficients have been determined. The effect of pH on the rate of reaction and the equilibrium composition has been investigated. The rate coefficients in water and in organic solvents correlate satisfactorily with the Dimroth-Reichardt solvent polarity parameter. The present results support the existence of a zwitterionic intermediate stabilized by polar solvents and show that protonation of the alkaloids inhibits the isomerization. The crystal structure of pteropodine has been determined.
