14035-81-5

Basic information

• Product Name: 3-ethyloxolane-2,5-dione
• Synonyms: 3-ethyloxolane-2,5-dione
• CAS NO: 14035-81-5
• Molecular Formula: C₆H₈O₃
• Molecular Weight: 0
• Mol File: 14035-81-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 242.1°Cat760mmHg
• Flash Point: 111°C
• Appearance: /
• Density: 1.161g/cm³
• Vapor Pressure: 0.0346mmHg at 25°C
• Refractive Index: 1.449
• CAS DataBase Reference: 3-ethyloxolane-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethyloxolane-2,5-dione(14035-81-5)
• EPA Substance Registry System: 3-ethyloxolane-2,5-dione(14035-81-5)

Safety Data

• Hazardous Substances Data: 14035-81-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H8O3/c1-2-4-3-5(7)9-6(4)8/h4H,2-3H2,1H3

Upstream product

• 687-28-5 S-(-)-2-ethylsuccinic acid 
• 636-48-6 monoethylsuccinic acid 
• 75-36-5 acetyl chloride 
• 151-50-8 potassium cyanide 
• 123-38-6 propionaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 
• 75-26-3 isopropyl bromide 
• 15890-55-8 β-valerolactone 
• 201230-82-2 carbon monoxide 
• 108-31-6 maleic anhydride 
• 1921-70-6 pristane 
• 3043-60-5 triethylboroxine 
• 106-88-7 ethyloxirane 
• 123475-49-0 3-(tert-butoxycarbonyl)pentanoic acid 

Downstream Products

• 107776-23-8 2-ethyl-4-(3-chloro-4-methoxy-phenyl)-4-oxo-butyric acid 
• 100119-60-6 2-ethyl-4-(5-chloro-2-hydroxy-phenyl)-4-oxo-butyric acid 
• 56615-45-3 2-ethyl-4-oxo-4-phenyl-butyric acid 
• 636-48-6 monoethylsuccinic acid 
• 106165-83-7 2-Ethyl-4-phenyl-penten-3-saeure-⁽¹⁾ 
• 102018-56-4 3-Benzoyl-2-aethyl-4-phenyl-buten-⁽³⁾-saeure 
• 70861-68-6 RuH(OCOCH(CH₂CH₃)CH₂CHO)(P(C₆H₅)3)3 

Relevant articles and documents

Synthesis of d-labeled and unlabeled ethyl succinic anhydrides and application to quantitative analysis of peptides by isotope differential mass spectrometry

Ethyl succinic anhydride and its d5-labeled version have been synthesized and applied to quantitative analysis of peptides in combination with MALDI or ESI mass spectrometry. These modifiers react with amino groups in the N-termini and lysine side chains in proteins, and therefore the combination of these modifiers was shown to be a useful tool for quantification of peptides and hence for proteomics research.

Succinic anhydrides from epoxides

Catalysts and methods for the double carbonylation of epoxides are disclosed. Each epoxide molecule reacts with two molecules of carbon monoxide to produce a succinic anhydride. The reaction is facilitated by catalysts combining a Lewis acidic species with a transition metal carbonyl complex. The double carbonylation is achieved in single process by using reaction conditions under which both carbonylation reactions occur without the necessity of isolating or purifying the product of the first carbonylation.

Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers

A series of benzoxathiin SERAMs was prepared. Minor modifications in the side chain or linker resulted in significant effects on biological activity, especially in uterine tissue. A series of dihydrobenzoxathiin SERAMs with alkylated pyrrolidine side chains or alkylated linkers was prepared. Minor modifications in the side chain or linker resulted in significant effects on biological activity, especially in uterine tissue.