636-48-6

Basic information

• Product Name: 2-ETHYLSUCCINIC ACID
• Synonyms: 2-ETHYLSUCCINIC ACID;2-Ethylbutanedioic acid;ethyl succinic acid;AKOS MSC-0138
• CAS NO: 636-48-6
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.14
• EINECS: 211-259-6
• Mol File: 636-48-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 83.5-85 °C
• Boiling Point: 250.7°C at 760 mmHg
• Flash Point: 119.7°C
• Appearance: /
• Density: 1.246g/cm³
• Vapor Pressure: 0.00674mmHg at 25°C
• Refractive Index: 1.473
• PKA: pK1:4.08(0) (25°C)
• CAS DataBase Reference: 2-ETHYLSUCCINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYLSUCCINIC ACID(636-48-6)
• EPA Substance Registry System: 2-ETHYLSUCCINIC ACID(636-48-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 636-48-6(Hazardous Substances Data)

Usage

General Description

2-Ethylsuccinic acid is a chemical compound with the molecular formula C6H10O4. It is a dicarboxylic acid found in certain plant species and is also produced synthetically for various industrial applications. 2-ETHYLSUCCINIC ACID is used as a building block in the synthesis of pharmaceuticals, polymers, and other specialty chemicals. It has been studied for its potential as a chiral resolving agent and a starting material for the preparation of biologically active molecules. Additionally, 2-ethylsuccinic acid has been investigated for its potential use as a corrosion inhibitor and as a component in biodegradable polymers.

InChI:InChI=1/C6H10O4/c1-2-4(6(9)10)3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)

Upstream product

• 51251-11-7 diethyl ethylsuccinate 
• 13074-60-7 monoethylmaleic acid 
• 5469-25-0 ethylfumaric acid 
• 5671-99-8 2-ethylidenesuccinic acid 
• 180331-63-9 2,3-dicyano-valeric acid ethyl ester 
• 10172-12-0 butane-1,1,2-tricarboxylic acid 
• 100316-04-9 2-acetyl-3-ethyl-succinic acid diethyl ester 
• 131590-31-3 butane-1,1,2-tricarboxylic acid triethyl ester 
• 472-08-2 digitogenic acid 
• 18017-40-8 2-ethyl-3-cyano-succinic acid diethyl ester 
• 91334-18-8 diethyl 2-(1-nitrobutan-2-yl)malonate 
• 25236-76-4 2-Ethyl-4,4,4-trichlor-ethylbutyrat 
• 923-06-8 bromosuccinic acid 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 4074-24-2 (R)-2-Ethylbutannedioic acid 
• 14035-81-5 ethylsuccinic anhydride 
• 15012-53-0 2-ethylnaphthazarin 
• 14035-95-1 (S)-dimethyl 2-ethylsuccinate 
• 14035-81-5 (S)-ethylsuccinic anhydride 

Relevant articles and documents

Direct and Selective Synthesis of Adipic and Other Dicarboxylic Acids by Palladium-Catalyzed Carbonylation of Allylic Alcohols

A general and direct synthesis of dicarboxylic acids including industrially important adipic acid by palladium-catalyzed dicarbonylation of allylic alcohol is reported. Specifically, the combination of PdCl2 and a bisphosphine ligand (HeMaRaphos) promotes two different carbonylation reactions with high activity and excellent selectivity.

Synthesis of d-labeled and unlabeled ethyl succinic anhydrides and application to quantitative analysis of peptides by isotope differential mass spectrometry

Ethyl succinic anhydride and its d5-labeled version have been synthesized and applied to quantitative analysis of peptides in combination with MALDI or ESI mass spectrometry. These modifiers react with amino groups in the N-termini and lysine side chains in proteins, and therefore the combination of these modifiers was shown to be a useful tool for quantification of peptides and hence for proteomics research.

Pentenoic acid hydroxycarbonylation method

The invention discloses pentenoic acid hydroxycarbonylation into adipic acid. More particularly, it concerns one pentenoic acid hydroxycarbonylation method involving reaction water and carbon monoxide, in the presence of a catalyst comprising at least rho